Prognostic Value of Albumin-to-Fibrinogen Ratio for 28-Day Mortality among Patients with Sepsis from Various Infection Sites

Purpose. This study investigated the prognostic value of the albumin-to-fibrinogen ratio (AFR) in patients with sepsis as a consequence of infection at various sites. Methods. A total of 300 patients with sepsis caused by various infection sites, who met the diagnostic criteria for sepsis hospitaliz...

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Bibliographic Details
Published in:Mediators of inflammation 2022-08, Vol.2022, p.1-9
Main Authors: Li, Shuai, Shen, Yawei, Chang, Bowen, Wang, Nan
Format: Article
Language:English
Subjects:
Age
Albumin
Analysis
Biomarkers
Blood
Body temperature
China
Data analysis
Diabetes
Fibrin
Fibrinogen
Gender
Heart rate
Hospitals
Hypertension
Infection
Infections
Inflammation
Kidney diseases
Laboratories
Lactic acid
Lung diseases
Medical prognosis
Medical research
Medicine, Experimental
Mortality
Patient outcomes
Patients
Prognosis
Renal replacement therapy
Sepsis
Septic shock
Taiwan
Tumors
Ventilators
Vital signs
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Summary:Purpose. This study investigated the prognostic value of the albumin-to-fibrinogen ratio (AFR) in patients with sepsis as a consequence of infection at various sites. Methods. A total of 300 patients with sepsis caused by various infection sites, who met the diagnostic criteria for sepsis hospitalized in the intensive care unit, were enrolled in this study. The observational endpoint was 28-day mortality. Cox proportional hazard regression analysis was performed to determine the potential prognostic factors for 28-day mortality in these septic patients. Receiver operating characteristic (ROC) curve analysis was used to evaluate and compare the prognostic factors for 28-day mortality. Results. Of 300 participants, 147 died, corresponding to a 28-day mortality of 49% (147/300). Baseline Acute Physiology and Chronic Health Evaluation (APACHE II) score (hazard ratio (HR) 1.18 (95% confidence interval (CI) 1.07–1.30); P
ISSN:0962-9351
1466-1861
DOI:10.1155/2022/3578528