Incidence and predictors of futile recanalisation after endovascular therapy in acute vertebrobasilar artery occlusion patients: insight from the ANGEL-ACT registry

ObjectivesTo identify the occurrence rate and predictors of futile recanalisation after endovascular therapy (EVT) for acute vertebrobasilar artery occlusion (VBAO).MethodsParticipants of the Endovascular Treatment Key Technique and Emergency Workflow Improvement of Acute Ischaemic Stroke (ANGEL-ACT...

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Published in:Stroke and vascular neurology 2024-06, Vol.9 (3), p.289-294
Main Authors: Sun, Dapeng, Yang, Xinguang, Huo, Xiaochuan, ‑, Raynald, Jia, Baixue, Tong, Xu, Wang, Anxin, Ma, Ning, Gao, Feng, Mo, Dapeng, Miao, Zhongrong
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anticoagulants
Asian people
Atherosclerosis
Blood platelets
Cardiovascular disease
Cerebral Infarction
Data collection
Disability Evaluation
Endovascular Procedures - adverse effects
Female
General anesthesia
Humans
Incidence
Ischemia
Lymphocytes
Male
Medical Futility
Medical imaging
Middle Aged
Missing data
Neutrophils
Original Research
Patients
Recovery of Function
Registries
Risk Assessment
Risk Factors
Statistical significance
Stroke
Thrombectomy
Time Factors
Treatment Outcome
Veins & arteries
Vertebrobasilar Insufficiency - diagnosis
Vertebrobasilar Insufficiency - diagnostic imaging
Vertebrobasilar Insufficiency - physiopathology
Vertebrobasilar Insufficiency - therapy
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Summary:ObjectivesTo identify the occurrence rate and predictors of futile recanalisation after endovascular therapy (EVT) for acute vertebrobasilar artery occlusion (VBAO).MethodsParticipants of the Endovascular Treatment Key Technique and Emergency Workflow Improvement of Acute Ischaemic Stroke (ANGEL-ACT) registry were selected for the analysis. Futile recanalisation was defined as patients did not achieve a 90-day good outcome (modified Rankin Scale ≤3) despite successful recanalisation (modified Treatment in Cerebral Ischaemia Scale ≥2b) after the procedure. Multivariable logistic regression analysis was conducted to find independent predictors of futile recanalisation in VBAO patients undergoing EVT.ResultsThree hundred and fifteen patients with VBAO who achieved successful recanalisation after EVT were included in current analysis, of whom, 155 (49.2%) suffered futile recanalisation, and 160 achieved effective recanalisation. After the multivariable analysis, we found admission National Institutes of Health Stroke Scale (NIHSS) ≥19 (OR 4.81, 95% CI 2.76 to 8.39, p
ISSN:2059-8688
2059-8696
2059-8696
DOI:10.1136/svn-2022-002185