Cerebral Small Vessel Disease

Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net of cerebral vessels, including small arteries, capillaries, arterioles and venules, is usually affected. Processes of oxidation underlie the p...

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Published in:International journal of molecular sciences 2020-12, Vol.21 (24), p.9729
Main Authors: Litak, Jakub, Mazurek, Marek, Kulesza, Bartłomiej, Szmygin, Paweł, Litak, Joanna, Kamieniak, Piotr, Grochowski, Cezary
Format: Article
Language:English
Subjects:
Arteries - pathology
Arterioles - pathology
Capillaries - pathology
Cerebellum - blood supply
Cerebellum - diagnostic imaging
Cerebellum - pathology
cerebral microbleeds
cerebral small vessel disease
Cerebral Small Vessel Diseases - diagnostic imaging
Cerebral Small Vessel Diseases - pathology
CMB
CSVD
Dementia, Vascular - diagnostic imaging
Dementia, Vascular - pathology
Humans
Magnetic Resonance Imaging
Review
Venules - pathology
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Summary:Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net of cerebral vessels, including small arteries, capillaries, arterioles and venules, is usually affected. Processes of oxidation underlie the pathology of CSVD, promoting the degenerative status of the epithelial layer. There are several classifications of cerebral small vessel diseases; some of them include diseases such as Binswanger's disease, leukoaraiosis, cerebral microbleeds (CMBs) and lacunar strokes. This paper presents the characteristics of CSVD and the impact of the current knowledge of this topic on the diagnosis and treatment of patients.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms21249729