Prooxidant-Antioxidant Balance in Umbilical Cord Blood of Infants with Meconium Stained of Amniotic Fluid

Objective. Using a novel assay termed prooxidant-antioxidant balance (PAB) assay to determine prooxidant-antioxidant balance in umbilical cord blood of infants with meconium stained of amniotic fluid (MSAF). Passage of meconium in amniotic fluid is associated with increase of neonatal mortality and...

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Bibliographic Details
Published in:Biochemistry Research International 2013-01, Vol.2013 (2013), p.61-64
Main Authors: Ahmad Shah, Farhat, Tara, Fatemeh, Arjmand, Mohammad Hassan, Hamidi Alamdari, Daryoush, Mosavi Bazaz, Mojtaba, Jalili, Amin, Saleh Moghadam, Masoud
Format: Article
Language:English
Subjects:
Amniotic fluid
Analysis
Chemical properties
Fetal blood
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Summary:Objective. Using a novel assay termed prooxidant-antioxidant balance (PAB) assay to determine prooxidant-antioxidant balance in umbilical cord blood of infants with meconium stained of amniotic fluid (MSAF). Passage of meconium in amniotic fluid is associated with increase of neonatal mortality and morbidity. This complication occurs in about 15% of infants and is more widespread in postterm neonates. About 1.5 percent of neonates with MSAF develop meconium aspiration syndrome. Method. Sera of 29 umbilical cord blood of infants with MSAF and 32 healthy infants (HI) were collected. Both groups had nonsmoker and non-alcoholic mothers with no diseases. The PAB was measured. Result. There was a significant increase of PAB value (32.8±15.9 HK) in umbilical cord blood of infants with MSAF in comparison to HI (24.5±12.6 HK) (P
ISSN:2090-2247
2090-2255
DOI:10.1155/2013/270545