Severe Gemella haemolysans endophthalmitis following ranibizumab intravitreal injection

Gemella haemolysans is a commensal of the upper respiratory tract that is rarely involved in ocular pathology. We present a unique case of endophthalmitis with negative cultures and positive 16s ribosomal ribonucleic acid gene sequencing showing G. haemolysans infection after an intravitreal ranibiz...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2017-11, Vol.65 (11), p.1249-1251
Main Authors: Salceanu, Silvia Olivia, Levy, Sarah, Cunningham, Richard, Frimpong-Ansah, Kwabena
Format: Article
Language:English
Subjects:
Age
Aged, 80 and over
Angiogenesis Inhibitors - therapeutic use
Anti-Bacterial Agents - therapeutic use
Antibiotics
Bacterial infections
Brief Communications
Cataracts
Complications and side effects
Consent
Dosage and administration
Drug therapy
Endocarditis
Endophthalmitis
Endophthalmitis - diagnosis
Endophthalmitis - microbiology
Endophthalmitis - therapy
Eye Infections, Bacterial - diagnosis
Eye Infections, Bacterial - microbiology
Eye Infections, Bacterial - therapy
Eye surgery
Female
Gemella - genetics
Gemella - isolation & purification
Gemella haemolysans
Glaucoma
Glucocorticoids - therapeutic use
Gram-positive bacteria
Gram-Positive Bacterial Infections - diagnosis
Gram-Positive Bacterial Infections - microbiology
Gram-Positive Bacterial Infections - therapy
Humans
Immunotherapy
Injection
Intravitreal Injections - adverse effects
Macular degeneration
Monoclonal antibodies
Nosocomial infections
Older people
Ophthalmology
Patients
Polymerase Chain Reaction
Ranibizumab
Ranibizumab - therapeutic use
Respiratory tract
Risk factors
RNA, Bacterial - genetics
RNA, Ribosomal, 16S - genetics
Staphylococcus
Staphylococcus epidermidis
Streptococcus
Vascular endothelial growth factor
Vascular Endothelial Growth Factor A - antagonists & inhibitors
Vitrectomy
Vitreous Body - microbiology
Wet Macular Degeneration - drug therapy
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Description
Summary:Gemella haemolysans is a commensal of the upper respiratory tract that is rarely involved in ocular pathology. We present a unique case of endophthalmitis with negative cultures and positive 16s ribosomal ribonucleic acid gene sequencing showing G. haemolysans infection after an intravitreal ranibizumab injection for wet age-related macular degeneration.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_1007_16