High‐Sensitive Cardiac Troponin I and Th1/Th2 Polarization in Queens With Pyometra

• Published in: Veterinary medicine and science 2025-01, Vol.11 (1), p.e70125-n/a
• Main Authors: Safak, Tarik, Saat, Nevzat, Yilmaz‐Koc, Oznur, Turanli, Mert, Ayalp‐Erkan, Aslıhan, Risvanli, Ali
• Format: Article
• Language: English
• Subjects: Abdomen; Animals; Aspartate aminotransferase; Bioassays; Cardiac muscle; Case-Control Studies; Cat Diseases - immunology; Cats; Creatine; Creatine kinase; Creatinine; Cytokines; Cytokines - metabolism; Dogs; E coli; Female; Hematology; high‐sensitive cardiac troponin I; Kinases; Laboratories; Lymphocytes T; Pathogens; Polarization; pyometra; Pyometra - metabolism; Pyometra - veterinary; queen; Queens; Sepsis; Statistical analysis; Th1 Cells - immunology; Th1/Th2 cytokine polarization; Th2 Cells - immunology; Troponin I; Troponin I - metabolism; Tumor necrosis factor-TNF; Ultrasonic imaging; Vagina
• ISSN: 2053-1095; 2053-1095
• DOI: 10.1002/vms3.70125

ABSTRACT Objectives To determine T helper (Th)1 and Th2 cytokine polarization, as well as high‐sensitive cardiac troponin I (hs‐cTnI) levels, in cats with pyometra. Methods We used 40 queens in the study. A total of 20 out of these 40 queens were diagnosed with the pyometra group (PYO) and the other 20 made up the healthy group (control; CTR). We measured concentrations of hs‐cTnI, aspartate aminotransferase (AST), creatine kinase (CK) and l‐lactate in queens from both groups. Additionally, we measured cytokine concentrations in all queens. Results The hs‐cTnI concentration in the PYO group (26.95 ± 5.08 ng/L) was significantly higher than that of the CTR group (7.00 ± 0.82 ng/L) (p