The Quartet Data Portal: integration of community-wide resources for multiomics quality control

The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins from the Quartet Project. Users can request DNA, RNA, protein, and metabolite reference mat...

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Bibliographic Details
Published in:Genome Biology 2023-10, Vol.24 (1), p.245-19, Article 245
Main Authors: Yang, Jingcheng, Liu, Yaqing, Shang, Jun, Chen, Qiaochu, Chen, Qingwang, Ren, Luyao, Zhang, Naixin, Yu, Ying, Li, Zhihui, Song, Yueqiang, Yang, Shengpeng, Scherer, Andreas, Tong, Weida, Hong, Huixiao, Xiao, Wenming, Shi, Leming, Zheng, Yuanting
Format: Article
Language:English
Subjects:
Biological analysis
Data analysis
Datasets
Genetic testing
Genomes
Genomics
Humans
Integration
Laboratories
Metabolites
Multiomics
Performance evaluation
Proteins
Proteomics
Quality Control
Quartet Data Portal
Quartet Project
Reference datasets
Reference materials
Software
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Summary:The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins from the Quartet Project. Users can request DNA, RNA, protein, and metabolite reference materials, as well as datasets generated across omics, platforms, labs, protocols, and batches. Reproducible analysis tools allow for objective performance assessment of user-submitted data, while interactive visualization tools support rapid exploration of reference datasets. A closed-loop "distribution-collection-evaluation-integration" workflow enables updates and integration of community-contributed multiomics data. Ultimately, this portal helps promote the advancement of reference datasets and multiomics quality control.
ISSN:1474-760X
1474-7596
1474-760X
DOI:10.1186/s13059-023-03091-9