Development and Evaluation of a Dual-Layer-Offset PET Detector Constructed with Different Reflectors

Dual-layer-offset or multi-layer-offset design of a PET detector can improve spatial resolution while maintaining high sensitivity. In this study, three dual-layer-offset LYSO detectors with three different reflectors (ESR, Toray, and BaSO4) were developed. The top layer consisted of a 17 × 17 array...

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Bibliographic Details
Published in:Crystals (Basel) 2022-01, Vol.12 (1), p.93
Main Authors: Zhang, Xi, Yu, Xin, Zhu, Zhiliang, Yu, Hongsen, Zhang, Heng, Zhang, Yibin, Gu, Zheng, Xu, Jianfeng, Peng, Qiyu, Xie, Siwei
Format: Article
Language:English
Subjects:
Algorithms
Aluminum
Arrays
Barite
Barium sulfate
Cables
Center of gravity
Crystals
Customization
Data processing
Design
Detectors
dual-layer-offset
Energy
Energy resolution
high resolution
Histograms
Light
Multilayers
PET detector
Positron emission
Reflectors
Scintillation counters
Sensors
Signal processing
Spatial resolution
Tomography
Valleys
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Summary:Dual-layer-offset or multi-layer-offset design of a PET detector can improve spatial resolution while maintaining high sensitivity. In this study, three dual-layer-offset LYSO detectors with three different reflectors (ESR, Toray, and BaSO4) were developed. The top layer consisted of a 17 × 17 array of crystals 1 × 1 × 6.5 mm3 in size and the bottom layer consisted of an 18 × 18 array of crystals 1 × 1 × 9.5 mm3 in size. Neither light guides nor optical glue were used between the two layers of crystals. A custom-designed electronics system, composed of a 6 × 6 SiPM array, two FPC cables, and a custom-designed data processing module, was used to read out signals. An optimized interaction-decoding algorithm using the center of gravity to determine the position and threshold of analog signals for timing methods was applied to generate decoding flood histograms. The detector performances, in terms of peak to valley ratio of the flood histograms and energy resolutions, were calculated and compared. The dual-layer-offset PET detector constructed with BaSO4 reflectors performed much better than the other two reflectors in both crystal identification and energy resolution. The average peak-to-valley ratio and the energy resolution were approximately 7 and 11%, respectively. In addition, the crystals in the bottom layer showed better performance at crystal identification than those in the top layer. This study can act as a reference providing guidance in choosing scintillator reflectors for multi-layer dedicated DOI detectors designed for small-animal PET imaging.
ISSN:2073-4352
2073-4352
DOI:10.3390/cryst12010093