Mycoplasma pneumoniae and Chlamydia spp. infection in community-acquired pneumonia, Germany, 2011-2012

Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are difficult to propagate, and can cause clinically indistinguishable disease patterns. During 2011-2012, we used molecular methods to test adult patients in Germany with confirmed CAP for infect...

Full description

Saved in:
Bibliographic Details
Published in:Emerging infectious diseases 2015-03, Vol.21 (3), p.426-434
Main Authors: Dumke, Roger, Schnee, Christiane, Pletz, Mathias W, Rupp, Jan, Jacobs, Enno, Sachse, Konrad, Rohde, Gernot
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
and
bacterial pneumonia
CAP
Chlamydia - classification
Chlamydia - genetics
Chlamydia infections
Chlamydial Pneumonia - epidemiology
Chlamydial Pneumonia - microbiology
Community-acquired infections
Community-Acquired Infections - epidemiology
Community-Acquired Infections - microbiology
community-acquired pneumonia
Complications and side effects
Demographic aspects
Female
Genotype
Germany - epidemiology
Humans
Incidence
Male
Middle Aged
MLVA
molecular diagnostics
Molecular Typing
Mycoplasma infections
Mycoplasma pneumoniae - classification
Mycoplasma pneumoniae - genetics
outpatients
Pneumonia, Mycoplasma - epidemiology
Pneumonia, Mycoplasma - microbiology
Risk factors
spp. Infection in Community-Acquired Pneumonia, Germany, 2011–2012
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are difficult to propagate, and can cause clinically indistinguishable disease patterns. During 2011-2012, we used molecular methods to test adult patients in Germany with confirmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and levels of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peak for these infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring conditions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemiology of these pathogens in CAP.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2103.140927