The Effect of Vitamin D Administration on Androgen Levels in Addition to Metformin Treatment in Adolescent Girls with Hyperandrogenism

This retrospective study was planned to examine the relationship between glucose metabolism, androgen and lipid profiles after vitamin D and metformin treatments in adolescent girls with hyperandrogenism. Forty-five adolescent female patients diagnosed with hyperandrogenism were divided into three g...

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Bibliographic Details
Published in:Journal of pediatric academy 2022-04, Vol.3 (1), p.26-31
Main Authors: Çiğ, Esranur, Atar, Muge, Pirgon, Ozgur
Format: Article
Language:English
Subjects:
hyperandrogenism, adolescent, vitamin d, metformin, testosterone
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Summary:This retrospective study was planned to examine the relationship between glucose metabolism, androgen and lipid profiles after vitamin D and metformin treatments in adolescent girls with hyperandrogenism. Forty-five adolescent female patients diagnosed with hyperandrogenism were divided into three groups. The first group of patients was given metformin (M), the second group was given metformin and vitamin D drops (MdD), and the third group were those who received oral metformin and vitamin D ampoules (MsD). Biochemical and hormonal parameters at the end of 8 weeks were compared statistically. The vitamin D level was higher in the metformin-vitamin D stoss treated group than metformin-vitamin D drops. There was a positive correlation between vitamin D and SHBG in the metformin group (r =0.65, p
ISSN:2718-0875
2718-0875
DOI:10.51271/jpea-2022-162