Occurrence and Risk Factors Associated with Platynosomum illiciens Infection in Cats with Elevated Liver Enzymes

spp., a hepatic trematode, causes fatal hepatobiliary disease in cats. Feline platynosomiasis is often underestimated due to a lack of awareness and diagnostic challenges. This study aimed to investigate the occurrence, factors, and clinicopathological abnormalities associated with spp. infection in...

Full description

Saved in:
Bibliographic Details
Published in:Animals (Basel) 2024-03, Vol.14 (7), p.1065
Main Authors: Chantawong, Pinkarn, Potiwong, Jiraporn, Choochote, Natchanon, Piyarungsri, Kakanang, Kunkaew, Chakorn, Tangtrongsup, Sahatchai, Tiwananthagorn, Saruda
Format: Article
Language:English
Subjects:
associated factors
Automation
Bile ducts
Cats
Eggs
Enzymes
Feces
Genetic testing
Infections
liver enzymes
liver fluke
Parasites
Phylogenetics
Platynosomum illiciens
Regression analysis
Risk factors
Software
Veterinary medicine
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:spp., a hepatic trematode, causes fatal hepatobiliary disease in cats. Feline platynosomiasis is often underestimated due to a lack of awareness and diagnostic challenges. This study aimed to investigate the occurrence, factors, and clinicopathological abnormalities associated with spp. infection in cats with elevated serum ALT levels. infection was determined using zinc sulfate flotation and formalin-ether sedimentation. DNA sequence analysis of PCR products from the internal transcribed spacer 2 (ITS2) region and gene was used to identify species. Of a total of 43 cat fecal samples, the proportion of spp. infection by microscopic examination was 11.63% (5/43). All PCR-positive samples were molecularly identified as . From the logistic regression analysis, the odds of infection in cats without a deworming program were 16 times higher than those of regularly dewormed cats. Demographic data, housing conditions, and predatory behavior were not significantly associated with the infection. Regarding blood profiles, infected cats had higher eosinophil counts ( = 0.014), with no significant differences in ALT ( = 0.791) or ALP ( = 0.970) levels compared to non-infected cats. Our findings demonstrate that eosinophilia in cats with increased serum ALT may suggest infection in endemic areas. We strongly recommend a regular deworming program to mitigate the risk of infection.
ISSN:2076-2615
2076-2615
DOI:10.3390/ani14071065