Evaluation of diaphragmatic mobility following intra-abdominal sub-diaphragmatic fixation of a double-layered mesh in rats

PURPOSE: To evaluate the tissue integration of a double-sided mesh after fixation in diaphragm and to study the diaphragmatic mobility by ultrasound. METHODS: Twenty male Wistar rats were used. The animals were assigned into two equal groups according to the day of euthanasia. The animals were anest...

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Bibliographic Details
Published in:Acta cirúrgica brasileira 2016-04, Vol.31 (4), p.235-242
Main Authors: Ioannis, Tzanoglou, George, Sakorafas, Nikolaos, Kostomitsopoulos, George, Mantziaras, Charalampos, Patraleksis, Nikolaos, Danias, Spyridon, Stergiopoulos, Michael, Safioleas
Format: Article
Language:English
Subjects:
Diaphragm
Fibrosis
Foreign-Body Reaction
Rats
Surgical Mesh
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Summary:PURPOSE: To evaluate the tissue integration of a double-sided mesh after fixation in diaphragm and to study the diaphragmatic mobility by ultrasound. METHODS: Twenty male Wistar rats were used. The animals were assigned into two equal groups according to the day of euthanasia. The animals were anesthetized and a 1.5 x 1.5 cm of double-layer mesh was inserted between the diaphragm and the liver. For the evaluation of the diaphragm mobility a sonographic method was used. Measurements on specific breathing parameters were taking place. Pathological evaluation took place after the animal's euthanasia. RESULTS: Extra-hepatic granuloma was not differentiated overtime, (χ2=0.04, p>0.05). Neither fibrosis was significantly differentiated, (χ2=0.04, p>0.05). Intra-hepatic granuloma was significantly differentiated overtime, (χ2=10.21, p
ISSN:0102-8650
0102-8650
DOI:10.1590/S0102-865020160040000003