A Case Report of a 3-Year-Old Child With Anaphylactic Shock After a Diclofenac Suppository Confirmed by Serial Tryptase and a Basophil Activation Test

Diclofenac is one of the most commonly used non-steroidal anti-inflammatory drug (NSAID) agents for fever management by general practitioners. Anaphylaxis due to suppository of diclofenac sodium (Voltaren) is extremely rare in children. We report the case of a 3-year-old girl with anaphylactic shock...

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Bibliographic Details
Published in:Frontiers in pediatrics 2022-02, Vol.9, p.802715
Main Authors: Huang, Wun-Yan, Chiu, Tsu-Man, Kuo, Su-Feng, Chung, Wen-Hung, Tsai, Yi-Giien
Format: Article
Language:English
Subjects:
anaphylaxis
basophil activation test
diclofenac
non-steroidal anti-inflammatory drug
Pediatrics
tryptase
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Summary:Diclofenac is one of the most commonly used non-steroidal anti-inflammatory drug (NSAID) agents for fever management by general practitioners. Anaphylaxis due to suppository of diclofenac sodium (Voltaren) is extremely rare in children. We report the case of a 3-year-old girl with anaphylactic shock after a diclofenac suppository with confirmation by serial tryptase and a basophil activation test.
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2021.802715