Association of overweight and obesity with coronary risk factors and the presence of multivessel disease in patients with obstructive coronary artery disease – A nationwide registry study

• Published in: International journal of cardiology. Cardiovascular risk and prevention 2024-09, Vol.22, p.200299-200299, Article 200299
• Main Authors: Pham, Maria Hang Xuan, Christensen, Daniel Mølager, Kristensen, Andreas Torp, Middelfart, Charlotte, Sindet-Pedersen, Caroline, Gislason, Gunnar, Olsen, Niels Thue
• Format: Article
• Language: English
• Subjects: Body mass index; Cardiovascular; Coronary artery disease; Obesity; Overweight; Research Paper; Risk factors
• ISSN: 2772-4875; 2772-4875
• DOI: 10.1016/j.ijcrp.2024.200299

AbstractBackgroundThe growing prevalence of obesity is expected to increase the burden of coronary artery disease. This study examined the prevalence of overweight and obesity in patients with a first-time diagnosis of obstructive coronary artery disease in a contemporary population. The association of body-mass-index (BMI) with age, traditional risk factors, and the presence of multivessel disease were explored. Methods and resultsUsing the Danish Nationwide registries, we identified 49,733 patients with a first-time diagnosis of obstructive coronary artery disease in the period 2012–2018. We investigated the association between BMI and coronary risk factors by multivariate logistic regression. Mean age was 65.8 ± 11.8 years, mean BMI was 27.5 kg/m 2 ± 7.2, and 73.2 % were men. 66.3 % had a BMI ≥25 kg/m 2 and 1.3 % were underweight. The prevalence of patients with BMI ≥25 kg/m 2 decreased with increasing age and was 69 % in patients