Factors influencing the reliability of measurements in eyes with full-thickness macular holes: are we measuring incorrectly?

PurposeThe calliper function is used for manual measurements of full thickness macular holes (FTMHs). We aimed to investigate whether a reproducible difference could be detected beyond interobserver variability between two commonly used manufacturers in their manual calliper facility in spectral dom...

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Bibliographic Details
Published in:BMJ open ophthalmology 2024-08, Vol.9 (1), p.e001531
Main Authors: Moussa, George, Jalil, Assad, Lippera, Myrta, Alnafisee, Nouf, Ivanova, Tsveta
Format: Article
Language:English
Subjects:
Aged
Clinical medicine
Female
Humans
Imaging
Macula
Male
Measurement techniques
Middle Aged
Observer Variation
Original Research
Reproducibility of Results
Retina
Retinal Perforations - diagnostic imaging
Retrospective Studies
Surgery
Surgical outcomes
Tomography
Tomography, Optical Coherence - methods
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Summary:PurposeThe calliper function is used for manual measurements of full thickness macular holes (FTMHs). We aimed to investigate whether a reproducible difference could be detected beyond interobserver variability between two commonly used manufacturers in their manual calliper facility in spectral domain optical coherence tomography (OCT) for metrics related to FTMH.MethodsThis is a non-interventional, retrospective, observational study. Two independent observers examined 8 eyes (16 OCT) scans and 128 measurements (minimal linear diameter (MLD), basal diameter and hole height on both sides) of FTMHs, taken on Heidelberg Spectralis and Topcon Triton (OCT machines). The interobserver agreement and OCT machine agreement of measurements were analysed by Bland-Altman plots and intraclass correlation coefficient (ICC) analysis. Spectralis and Triton had 125 µm and 50 µm horizontal b-scan spacing, respectively.ResultsOverall, we report high absolute agreement in interobserver (ICC 0.991 (95% CI 0.985 to 0.995, p
ISSN:2397-3269
2397-3269
DOI:10.1136/bmjophth-2023-001531