Prospective assessment of VI-RADS score in multiparametric MRI in bladder cancer: accuracy and the factors affecting the results

• Published in: Diagnostic and interventional radiology (Ankara, Turkey) Turkey), 2022-09, Vol.28 (5), p.396-402
• Main Authors: Oğuz, Ural, Bekçi, Tümay, Öğreden, Ercan, Aslan, Serdar, Duman, Aslıhan, Demirelli, Erhan, Şengül, Demet, Tok, Doğan Sabri, Çiftçi, Osman Çağatay, Tosun, Alptekin
• Format: Article
• Language: English
• Subjects: Bladder cancer; Data Systems; Diagnosis; Evaluation; Humans; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Medical protocols; Multiparametric Magnetic Resonance Imaging; Predictive Value of Tests; Prospective Studies; Urinary Bladder Neoplasms - diagnostic imaging; Urinary Bladder Neoplasms - pathology
• ISSN: 1305-3825; 1305-3612
• DOI: 10.5152/dir.2022.201108

PURPOSE We aimed to investigate the accuracy of Vesical Imaging - Reporting and Data System (VI-RADS) in the detection of muscle-invasive bladder cancer (MIBC) and to determine which factors affect the results of this scoring system. METHODS A prospective data analysis of 80 patients who were detected to have bladder tumor was performed between March 2019 and October 2020. VI-RADS scoring was used to determine the probability of muscle invasion. The scores were compared with pathological results to evaluate the accuracy of the VI-RADS scoring system. Interobserver agreement was assessed by VI-RADS scoring of 20 randomly chosen patients by a different experienced radiologist. RESULTS Using the VI-RADS scoring system, the sensitivity, specificity, positive predictive value, and negative predictive value of multiparametric magnetic resonance imaging (mpMRI) were 87.5%, 87.5%, 63.6%, and 96.6%, respectively. The interobserver agreement expressed as the interclass correlation coefficient (ICC) was 0.72 (95% CI: 0.44-0.84, P < .001). In addition, the flat appearance of the tumor was an important factor affecting the accuracy of the VI-RADS score (odds ratio: 5.3 [95% CI: 1.1-27.0] and relative risk: 1.87 [95% CI: 1.24-2.82]). CONCLUSION The mpMRI, used in conjunction with VI-RADS, has proven to be an effective imaging method for detecting muscle invasion in cases of bladder cancer. VI-RADS scoring system can distinguish whether there is a muscle-invasive and non-muscle invasive bladder cancer with acceptable accuracy. In addition, the flat appearance of the tumor is an important entity that can affect the accuracy of the VI-RADS scoring system.