Transforming growth factor Beta leucine10 proline variation and breast cancer risk in Iranian women

[...]the more tumors advance, the more TGF-β1 express, which can be associated with phenotype and impaired clinical feature of this disease (3). [...]defining TGF-β molecular mechanisms and its involvement in the process of carcinogenesis is a major challenge. According to these results, we investig...

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Bibliographic Details
Published in:Iranian journal of public health 2015-03, Vol.44 (3), p.427-429
Main Authors: Dehghan Tezerjani, Masoud, Beik, Mahdi, Kalantar, Seyed Milad, Rasti, Azam, Kalantar, Seyed Mehdi, Shiryazdi, Seyed Mostafa
Format: Article
Language:English
Subjects:
Breast cancer
Cell division
Cytokines
Deoxyribonucleic acid
DNA
Genes
Genotype & phenotype
Letter to the Editor
Mutation
Polymerase chain reaction
Studies
Womens health
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Summary:[...]the more tumors advance, the more TGF-β1 express, which can be associated with phenotype and impaired clinical feature of this disease (3). [...]defining TGF-β molecular mechanisms and its involvement in the process of carcinogenesis is a major challenge. According to these results, we investigated whether TGFβ1 gene polymorphism in codon 10 is associated with Breast cancer in Iranian population.
ISSN:2251-6085
2251-6093