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Lawsonia intracellularis in a dog with inflammatory bowel disease
A two-year-old male German short-haired pointer was presented with a 1.5-year history of intermittent small-bowel diarrhoea. Inflammatory bowel disease (chronic lymphocytic-plasmacytic gastritis, enteritis and colitis) was diagnosed on the basis of histological examination of biopsies obtained on re...
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Published in: | Veterinární medicína 2003-05, Vol.48 (5), p.141-145 |
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creator | Husnik, R., Klimes, J., Tomanova, K., Smola, J., Halouzka, R., Tichy, F., Brazdil, J. (Veterinarni a Farmaceuticka Univ., Brno (Czech Republic)) |
description | A two-year-old male German short-haired pointer was presented with a 1.5-year history of intermittent small-bowel diarrhoea. Inflammatory bowel disease (chronic lymphocytic-plasmacytic gastritis, enteritis and colitis) was diagnosed on the basis of histological examination of biopsies obtained on repeated endoscopy and by exclusion of other possible causes. Warthin-Starry silver staining of stomach mucosa revealed the presence of gastric spiral organisms. The evidence of L. intracellularis was provided by a positive nested polymerase chain reaction in one biopsy of duodenal mucosa and in one rectal smear. In 5 blood sera collected over a period of 8 months the IgG antibodies to L. intracellularis were found by an indirect fluorescent antibody test. Treatment with oral prednisone led only to a temporary improvement. |
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(Veterinarni a Farmaceuticka Univ., Brno (Czech Republic))</creator><creatorcontrib>Husnik, R., Klimes, J., Tomanova, K., Smola, J., Halouzka, R., Tichy, F., Brazdil, J. (Veterinarni a Farmaceuticka Univ., Brno (Czech Republic))</creatorcontrib><description>A two-year-old male German short-haired pointer was presented with a 1.5-year history of intermittent small-bowel diarrhoea. Inflammatory bowel disease (chronic lymphocytic-plasmacytic gastritis, enteritis and colitis) was diagnosed on the basis of histological examination of biopsies obtained on repeated endoscopy and by exclusion of other possible causes. Warthin-Starry silver staining of stomach mucosa revealed the presence of gastric spiral organisms. The evidence of L. intracellularis was provided by a positive nested polymerase chain reaction in one biopsy of duodenal mucosa and in one rectal smear. In 5 blood sera collected over a period of 8 months the IgG antibodies to L. intracellularis were found by an indirect fluorescent antibody test. Treatment with oral prednisone led only to a temporary improvement.</description><identifier>ISSN: 0375-8427</identifier><identifier>EISSN: 1805-9392</identifier><identifier>DOI: 10.17221/5761-VETMED</identifier><language>eng</language><publisher>Prague: Czech Academy of Agricultural Sciences (CAAS)</publisher><subject>Antibodies ; BIOPSIA ; BIOPSIE ; BIOPSY ; CHIEN ; CHRONIC COURSE ; chronic gastritis ; COLITE ; COLITIS ; DIARREA ; Diarrhea ; DIARRHOEA ; DIARRHÉE ; dog ; DOGS ; ENDOSCOPIE ; ENDOSCOPY ; ENDOSCOPÍA ; ENTERITIS ; ENTERÍTIS ; ENTÉRITE ; Fluorescence ; Fluorescent antibody test ; GASTRITE ; GASTRITIS ; GASTRÍTIS ; GLUCOCORTICOIDES ; GLUCOCORTICOIDS ; GLUCOCORTICOÏDE ; HISTOPATHOLOGIE ; HISTOPATHOLOGY ; HISTOPATOLOGÍA ; Immunoglobulin G ; Indirect fluorescent antibody test ; Inflammatory bowel disease ; Inflammatory bowel diseases ; LAWSONIA INTRACELLULARIS ; Mucosa ; nested polymerase chain reaction ; PCR ; PERRO ; Polymerase chain reaction ; Prednisone ; PROCESO CRÓNICO ; PROCESSUS CHRONIQUE ; Rectum ; Small intestine ; SYMPTOME ; SYMPTOMS ; SÍNTOMAS ; TERAPIA ; THERAPY ; THÉRAPEUTIQUE</subject><ispartof>Veterinární medicína, 2003-05, Vol.48 (5), p.141-145</ispartof><rights>2003. 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Treatment with oral prednisone led only to a temporary improvement.</description><subject>Antibodies</subject><subject>BIOPSIA</subject><subject>BIOPSIE</subject><subject>BIOPSY</subject><subject>CHIEN</subject><subject>CHRONIC COURSE</subject><subject>chronic gastritis</subject><subject>COLITE</subject><subject>COLITIS</subject><subject>DIARREA</subject><subject>Diarrhea</subject><subject>DIARRHOEA</subject><subject>DIARRHÉE</subject><subject>dog</subject><subject>DOGS</subject><subject>ENDOSCOPIE</subject><subject>ENDOSCOPY</subject><subject>ENDOSCOPÍA</subject><subject>ENTERITIS</subject><subject>ENTERÍTIS</subject><subject>ENTÉRITE</subject><subject>Fluorescence</subject><subject>Fluorescent antibody test</subject><subject>GASTRITE</subject><subject>GASTRITIS</subject><subject>GASTRÍTIS</subject><subject>GLUCOCORTICOIDES</subject><subject>GLUCOCORTICOIDS</subject><subject>GLUCOCORTICOÏDE</subject><subject>HISTOPATHOLOGIE</subject><subject>HISTOPATHOLOGY</subject><subject>HISTOPATOLOGÍA</subject><subject>Immunoglobulin G</subject><subject>Indirect fluorescent antibody test</subject><subject>Inflammatory bowel disease</subject><subject>Inflammatory bowel diseases</subject><subject>LAWSONIA INTRACELLULARIS</subject><subject>Mucosa</subject><subject>nested polymerase chain reaction</subject><subject>PCR</subject><subject>PERRO</subject><subject>Polymerase chain reaction</subject><subject>Prednisone</subject><subject>PROCESO CRÓNICO</subject><subject>PROCESSUS CHRONIQUE</subject><subject>Rectum</subject><subject>Small intestine</subject><subject>SYMPTOME</subject><subject>SYMPTOMS</subject><subject>SÍNTOMAS</subject><subject>TERAPIA</subject><subject>THERAPY</subject><subject>THÉRAPEUTIQUE</subject><issn>0375-8427</issn><issn>1805-9392</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNo9kE1rGzEQhkVoIG6SW66BhV676eh7dQyu2wZccnFyyEWMtFp3zdpypTXG_76Kt-Q0vMPDO8NDyB2FB6oZo9-kVrR-Xax-L75fkBltQNaGG_aJzIBrWTeC6SvyOecNADMUzIw8LvGY467Hqt-NCX0YhsOAqc8lV1i1cV0d-_FPSd2A2y2OMZ0qF49hqNo-B8zhhlx2OORw-39ek5cfi9X8V718_vk0f1zWnjd6rDvHwbggRJmCCa9b55nkgnMagLbQccUUSG0od2BKdEwzpK2HwAMqxq_J09TbRtzYfeq3mE42Ym_Pi5jWFtPY-yFY6WUrFQTHlBCN041hXHrvmlapJgRfur5MXfsU_x5CHu0mHtKuvG-ZBK24Eo0q1NeJ8inmnEL3cZWCPQu378LtJLzg9xPeYbS4Lg7t_I0BcAAwXPF_owJ6bg</recordid><startdate>20030501</startdate><enddate>20030501</enddate><creator>Husnik, R., Klimes, J., Tomanova, K., Smola, J., Halouzka, R., Tichy, F., Brazdil, J. 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subjects | Antibodies BIOPSIA BIOPSIE BIOPSY CHIEN CHRONIC COURSE chronic gastritis COLITE COLITIS DIARREA Diarrhea DIARRHOEA DIARRHÉE dog DOGS ENDOSCOPIE ENDOSCOPY ENDOSCOPÍA ENTERITIS ENTERÍTIS ENTÉRITE Fluorescence Fluorescent antibody test GASTRITE GASTRITIS GASTRÍTIS GLUCOCORTICOIDES GLUCOCORTICOIDS GLUCOCORTICOÏDE HISTOPATHOLOGIE HISTOPATHOLOGY HISTOPATOLOGÍA Immunoglobulin G Indirect fluorescent antibody test Inflammatory bowel disease Inflammatory bowel diseases LAWSONIA INTRACELLULARIS Mucosa nested polymerase chain reaction PCR PERRO Polymerase chain reaction Prednisone PROCESO CRÓNICO PROCESSUS CHRONIQUE Rectum Small intestine SYMPTOME SYMPTOMS SÍNTOMAS TERAPIA THERAPY THÉRAPEUTIQUE |
title | Lawsonia intracellularis in a dog with inflammatory bowel disease |
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