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Lawsonia intracellularis in a dog with inflammatory bowel disease

A two-year-old male German short-haired pointer was presented with a 1.5-year history of intermittent small-bowel diarrhoea. Inflammatory bowel disease (chronic lymphocytic-plasmacytic gastritis, enteritis and colitis) was diagnosed on the basis of histological examination of biopsies obtained on re...

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Published in:Veterinární medicína 2003-05, Vol.48 (5), p.141-145
Main Author: Husnik, R., Klimes, J., Tomanova, K., Smola, J., Halouzka, R., Tichy, F., Brazdil, J. (Veterinarni a Farmaceuticka Univ., Brno (Czech Republic))
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description A two-year-old male German short-haired pointer was presented with a 1.5-year history of intermittent small-bowel diarrhoea. Inflammatory bowel disease (chronic lymphocytic-plasmacytic gastritis, enteritis and colitis) was diagnosed on the basis of histological examination of biopsies obtained on repeated endoscopy and by exclusion of other possible causes. Warthin-Starry silver staining of stomach mucosa revealed the presence of gastric spiral organisms. The evidence of L. intracellularis was provided by a positive nested polymerase chain reaction in one biopsy of duodenal mucosa and in one rectal smear. In 5 blood sera collected over a period of 8 months the IgG antibodies to L. intracellularis were found by an indirect fluorescent antibody test. Treatment with oral prednisone led only to a temporary improvement.
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subjects Antibodies
BIOPSIA
BIOPSIE
BIOPSY
CHIEN
CHRONIC COURSE
chronic gastritis
COLITE
COLITIS
DIARREA
Diarrhea
DIARRHOEA
DIARRHÉE
dog
DOGS
ENDOSCOPIE
ENDOSCOPY
ENDOSCOPÍA
ENTERITIS
ENTERÍTIS
ENTÉRITE
Fluorescence
Fluorescent antibody test
GASTRITE
GASTRITIS
GASTRÍTIS
GLUCOCORTICOIDES
GLUCOCORTICOIDS
GLUCOCORTICOÏDE
HISTOPATHOLOGIE
HISTOPATHOLOGY
HISTOPATOLOGÍA
Immunoglobulin G
Indirect fluorescent antibody test
Inflammatory bowel disease
Inflammatory bowel diseases
LAWSONIA INTRACELLULARIS
Mucosa
nested polymerase chain reaction
PCR
PERRO
Polymerase chain reaction
Prednisone
PROCESO CRÓNICO
PROCESSUS CHRONIQUE
Rectum
Small intestine
SYMPTOME
SYMPTOMS
SÍNTOMAS
TERAPIA
THERAPY
THÉRAPEUTIQUE
title Lawsonia intracellularis in a dog with inflammatory bowel disease
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