Clinical Characteristics of Hospital Follow-up for Patients Hospitalized from SARS CoV-2 (COVID 19) in an Academic Outpatient Internal Medicine Clinic

• Published in: Journal of primary care & community health 2022, Vol.13, p.21501319221134560
• Main Authors: Abohelwa, Mostafa, Peterson, Christopher J., Landis, Dylan, Le, Duc, Conde, Camila, DeWare, Charles, Elgendy, Fares, Payne, Drew, Nugent, Kenneth
• Format: Article
• Language: English
• Subjects: Adult; Aged; Chest; Cohort analysis; Coronaviruses; COVID-19; Diabetes; Dyspnea; Edema; Female; Ferritin; Follow-Up Studies; Health sciences; Hospitalization; Hospitals; Humans; Hypertension; Internal medicine; Long term symptoms; Lower limbs; Male; Middle Aged; Original Research; Outpatients; Paresthesia; Psychological problems; Race; Retrospective Studies; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Symptoms; Telemedicine; X-rays
• ISSN: 2150-1319; 2150-1327; 2150-1327
• DOI: 10.1177/21501319221134560

Background: As of July 2022, there have been more than 91.3 million cases of COVID-19 and nearly 1.03 million deaths in the United States alone. In addition, many people who survived COVID-19 had long-term symptoms, such as fatigue, dyspnea, loss of smell and taste, depression, and anxiety. Objectives: The purpose of our study is to evaluate the status of COVID-19 patients who were previously hospitalized. Methods: We conducted a single-center retrospective cohort study at Texas Tech University Health Sciences Center and its affiliated University Medical Center under IRB of L21-144. We included all patients hospitalized for COVID-19 and followed up in our Internal Medicine Clinic at any time between April 1, 2020, and April 1, 2021, and reviewed follow-up data for these patients after discharge. Results: A total of 128 patients were included; 59 (46%) were men, and 69 (54%) were women with an average age of 59.7 ± 14.8 years. Most of the patients (n = 78, 60.9%) identified their race as Hispanic or Latino origin; the next largest group was Caucasian (n = 29, 22.65%). The average number of days until post-hospitalization follow-up was 36 ± 38 days. The 50% of the patients (n = 64) used telemedicine for follow-up visits. Important comorbidities in these patients included diabetes (n = 84, 65.6%) and hypertension (n = 94, 73.4%). Thirty-four patients (26.6%) reported respiratory symptoms at their follow-up appointments, 24 patients (18.8%) reported constitutional symptoms, 12 patients (9.4%) reported GI symptoms, and 25 patients (19.5%) reported other symptoms, such as paresthesia, lower extremity edema, or psychological symptoms. After hospital discharge, 54 patients had follow-up chest x-rays, and 41 (75.9%) still had abnormal findings consistent with COVID-19 imaging characteristics. Follow-up laboratory tests identified 44 patients (77.2%, 57 tested) with elevated D-dimer levels, 44 patients (78.6%, 56 tested) with high ferritin levels, and 21patients (35.6%, 59 tested) with elevated troponin T HS levels. Conclusion: Long-lasting COVID-19 symptoms in these patients included respiratory symptoms (26.6%), constitutional symptoms (18.8%), GI symptoms (9.4%), and other symptoms, such as paresthesia, lower extremity edema, or psychological symptoms (19.5%). The rate of telehealth follow-up was 50%. Many patients had elevated inflammatory markers that will need follow up to determine the clinical implications.