Cytomegalovirus Colitis Masquerading as Apple-Core Lesion after Systemic Chemotherapy in a Patient with Relapsed Acute Myeloid Leukemia

We report the case of a 71-year-old male with relapsed acute myeloid leukemia who developed cytomegalovirus (CMV) colitis presenting as an apple-core lesion during induction chemotherapy. CMV infection occurs rarely during induction chemotherapy for acute myeloid leukemia. CMV infection is usually o...

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Bibliographic Details
Published in:Case reports in oncological medicine 2018-01, Vol.2018 (2018), p.1-4
Main Authors: Baur, Russell, Brady, Robert, Stockinger, Theresa, Barker, Darrell, Brownell, Jason, An, Jong, Cebe, Katherine
Format: Article
Language:English
Subjects:
Abdomen
Bone marrow
Cancer
Cancer therapies
Case Report
Case reports
Chemotherapy
Colitis
Colonoscopy
Colorectal cancer
Cytomegalovirus
Cytomegalovirus infections
Deoxyribonucleic acid
Development and progression
Diseases
DNA
Family medical history
Fever
Gastrointestinal diseases
Immunosuppressive agents
Infection
Infections
Infectious diseases
Inflammatory bowel disease
Leukemia
Mortality
Neutropenia
Patients
Relapse
Stem cells
Tazobactam
Transplantation
Transplantation of organs, tissues, etc
Ventilators
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Summary:We report the case of a 71-year-old male with relapsed acute myeloid leukemia who developed cytomegalovirus (CMV) colitis presenting as an apple-core lesion during induction chemotherapy. CMV infection occurs rarely during induction chemotherapy for acute myeloid leukemia. CMV infection is usually observed in patients with acquired immune deficiency syndrome (AIDS) and in those on immunosuppressive agents following bone marrow transplant. Although rare, CMV colitis should be considered in patients who are critically ill after systemic chemotherapy as it can cause significant morbidity and mortality.
ISSN:2090-6706
2090-6714
DOI:10.1155/2018/5683417