Faciobrachial dystonic seizure-like events in a patient with subacute sclerosing panencephalitis

Faciobrachial dystonic seizure is a distinctive phenomenology that is considered pathognomonic of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated autoimmune limbic encephalitis. However, similar phenomenology has been described with other neurological disorders as well. Here, we...

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Bibliographic Details
Published in:Annals of movement disorders 2022-05, Vol.5 (2), p.121-124
Main Authors: Vikram V Holla, Sudhakar Pushpa Chaithra, Shweta Prasad, Nitish Kamble, Pramod Kumar Pal, Ravi Yadav
Format: Article
Language:English
Subjects:
faciobrachial dystonic seizure
leucine-rich glioma-inactivated protein 1
myoclonus
subacute sclerosing panencephalitis
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Summary:Faciobrachial dystonic seizure is a distinctive phenomenology that is considered pathognomonic of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated autoimmune limbic encephalitis. However, similar phenomenology has been described with other neurological disorders as well. Here, we report the case of a 26-year-old man with subacute sclerosing panencephalitis who presented with multiple episodes of involuntary movements resembling faciobrachial dystonic seizure. Serum and cerebrospinal fluid autoimmune encephalitis panel, including leucine-rich glioma-inactivated protein 1 antibody, were negative. Classical periodic stereotypical slow wave discharges on the electroencephalogram and raised measles antibody titre in cerebrospinal fluid confirmed the diagnosis of subacute sclerosing panencephalitis.
ISSN:2590-3446
2590-3454
DOI:10.4103/AOMD.AOMD_41_21