Antioxidant and anti-inflammatory properties of “Limolanii” grass and perceptions of locals on its survival in the era of changing climate

• Published in: Heliyon 2022-12, Vol.8 (12), p.e12018-e12018, Article e12018
• Main Authors: Limantol, Andrew M., Agbemade, Blessed, Boamah, Vivian E., Badu, Mercy, Amponsah, Kingsley I., Adam, Firdaws C.N., Mohammed, Rahmatu B.
• Format: Article
• Language: English
• Subjects: Anti-inflammatory; Anti-nutritional factors; Antioxidant; Climate change perception; Limolanii; Local spice; Nutritional factors
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2022.e12018

The aromatic Spear grass Hyparrhena rufa (locally called “Limolanii”) found in the Saboba District of the Northern Region of Ghana is ingeniously used for dietary, medicinal, and other purposes. Focus group discussions were conducted in communities where “Limolanii” grows to assess the local perception of the importance of the grass and changing climate impacts on its continued existence. Findings indicated that the plant is of immense importance to the locals but has not been validated scientifically and reported for its current use. The communities are also hopeful of future socio-economic benefits of "Limolanii" but expressed concern about the lack of remediation practices to address issues of climate change, increased use of agrochemicals, urbanization, etc., which can lead to the extinction of the grass. “Limolanii” was therefore evaluated for its nutritional and anti-nutritional content by proximate analysis and ethanolic extract evaluated for some medicinal properties. The extract was assessed for its anti-inflammatory property using the carrageenan-induced oedema in chicks’ model while antioxidant property evaluated using DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity, Phosphomolybdenum (Total Antioxidant Capacity), Total Phenol (Folin-Ciocalteu), and Total Flavonoid Content (Aluminium-chloride colorimetric) assays. The plant showed good nutritional content, extract exhibited a dose-dependent inhibition of oedema with maximal percentage inhibition of 41.05% at 300 mg/kg body weight and noticeable antioxidant activities. Flavonoids, coumarins, and other phytochemicals detected in the plant could be responsible for these activities, however, at certain levels, these phytochemicals could act as anti-nutrients. “Limolanii” exhibits medicinal properties backing its use traditionally as food supplements and herbs, hence the need to explore its possible commercial cultivation and embark on community sensitization to encourage people to protect and expand its production. Nutritional factors; Anti-nutritional factors; Antioxidant; Anti-inflammatory; Local spice; Climate change perception; Limolanii.