Case Report: Metachronous Quadruple Cancers Including Breast Cancer and Triple Genital Cancer

Most multiple primary cancers(MPCs) are double primaries, while quadruple cancer is rare, especially breast cancer and triple genital cancer. Our work is the first report about ametachronous quadruple cancer in the reproductive system, including breast, ovary, fallopian tube and cervix. A54-year-old...

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Bibliographic Details
Published in:International journal of general medicine 2020-01, Vol.13, p.1575-1580
Main Authors: Bai, Jing, Xie, Zhaoguang, Sun, Li
Format: Article
Language:English
Subjects:
Breast cancer
Cancer
Cancer therapies
Case Report
Cervix
Chemotherapy
Development and progression
Endometrium
Fallopian tubes
genital cancer
Health aspects
Histochemistry
Lymphatic system
Medical diagnosis
Medical imaging
Medical research
Medicine, Experimental
metachronous cancer
Metastasis
multiple primary carcinoma
Ovarian cancer
quadruple cancer
Radiation therapy
Reproductive system
Squamous cell carcinoma
Tumors
Vagina
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Summary:Most multiple primary cancers(MPCs) are double primaries, while quadruple cancer is rare, especially breast cancer and triple genital cancer. Our work is the first report about ametachronous quadruple cancer in the reproductive system, including breast, ovary, fallopian tube and cervix. A54-year-old woman, who underwent modified radical mastectomy and right breast tumor resection 3 years ago, presented with abnormal vaginal discharge for 2 months, and she was subsequently diagnosed with stage IIA2 cervical squamous cell carcinoma. She then underwent radiotherapy and chemotherapy, as well as radical hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic lymphadenectomy. Postoperative pathological findings revealed that the patient had cervical, ovarian and tubal triple cancers with different histopathology for all lesions, also different from breast cancer, implying that these tumors had separate etiology and were not metastatic tumors. Our work might provide aseries of diagnostic, etiological and therapeutic strategies for MPC patients.
ISSN:1178-7074
1178-7074
DOI:10.2147/IJGM.S278219