An Unusual Case of Locally Advanced Glycogen-Rich Clear Cell Carcinoma of the Breast

Glycogen-rich clear cell (GRCC) is a rare subtype of breast carcinoma characterized by carcinoma cells containing an optically clear cytoplasm and intracytoplasmic glycogen. We present the case of a 55-year-old woman with a palpable mass in the right breast and clinical signs of locally advanced bre...

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Bibliographic Details
Published in:Case reports in oncology 2011-09, Vol.4 (3), p.452-457, Article 452
Main Authors: Martín-Martín, Beatriz, Berná-Serna, Juan D., Sánchez-Henarejos, Pilar, López-Poveda, María J., Berná-Mestre, Juan D., Rodríguez-García, José R.
Format: Article
Language:English
Subjects:
Glycogen-rich clear cell carcinoma
Locally advanced breast cancer
Mammography
Published: September 2011
Ultrasonography
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Summary:Glycogen-rich clear cell (GRCC) is a rare subtype of breast carcinoma characterized by carcinoma cells containing an optically clear cytoplasm and intracytoplasmic glycogen. We present the case of a 55-year-old woman with a palpable mass in the right breast and clinical signs of locally advanced breast cancer (LABC). The diagnosis of GRCC carcinoma was based on certain histopathological characteristics of the tumor and immunohistochemical analysis. To our knowledge, this is the first case of GRCC LABC with intratumoral calcifications. There is no evidence of recurrence or metastatic disease after 14 months’ follow-up.
ISSN:1662-6575
1662-6575
DOI:10.1159/000332044