Global acute malnutrition is associated with geography, season and malaria incidence in the conflict-affected regions of Ouham and Ouham Pendé prefectures, Central African Republic

• Published in: BMC medicine 2024-09, Vol.22 (1), p.380-16, Article 380
• Main Authors: Stambach, Nicola, Lambert, Helen, Eves, Katie, Nfornuh, Blaise Alenwi, Bowler, Emily, Williams, Peter, Lama, Marcel, Bakamba, Pascal, Allan, Richard
• Format: Article
• Language: English
• Subjects: Arm circumference; Armed Conflicts; Central African Republic; Central African Republic - epidemiology; Child, Preschool; Children; Community health workers; Complications and side effects; Conflict; Data analysis; Data collection; Displaced persons; Election results; Environmental aspects; Female; Food security; Geography; Health aspects; Health care; Health care access; Health services; Humanitarianism; Humans; Incidence; Infant; Malaria; Malaria - epidemiology; Male; Malnutrition; Malnutrition - epidemiology; Medical diagnosis; Medical personnel; Medical research; Medicine, Experimental; Meteorological data; Mortality; Nutrition; Nutrition surveys; Nutritional Status; Physiological aspects; Presidential elections; Rainy season; Risk factors; Seasons; Social aspects; Vector-borne diseases
• ISSN: 1741-7015; 1741-7015
• DOI: 10.1186/s12916-024-03603-9

Ongoing conflict between multiple armed groups, including pastoralist herders in the Central African Republic (CAR) causes frequent population displacements, food insecurity and scarcity of healthcare services. The inaccessibility and insecurity of many areas of CAR limit data collection and assessments from national nutritional surveys. Community health workers (CHWs) trained by an international non-governmental organisation, The MENTOR Initiative, deliver basic healthcare to children under 5 years old living in hard-to-reach and conflict-affected areas in eight subprefectures of north-west CAR. Their nutritional status and its associations with geography, malaria, season and conflict are unknown. CHW monthly records (October 2015-August 2021), Armed Conflict Location and Event Data project conflict data and The World Bank Group meteorological data for eight subprefectures of north-west CAR were analysed. Associations between counts of global acute malnutrition (GAM) assessed by mid-upper arm circumference and malaria, season and conflict were investigated using negative binomial regression. Of the 457,325 consultations with children aged 6-59 months, 6.2% and 0.4% were classified as moderately or severely malnourished, respectively. The negative binomial model demonstrated differences in counts of GAM by subprefecture. Counts of GAM were positively associated with the case rate of severe malaria (IRR = 1.045; 95% CI: 1.04-1.06) and the rainy season (July-September) (IRR = 1.10; 95% CI: 1.03-1.17). Conflict events coded as Battles in ACLED were associated with lower counts of GAM (IRR = 0.78; 95% CI: 0.62-0.97). This analysis shows geographical differences in levels of malnutrition in north-west CAR and demonstrates clear associations between malnutrition, season and malaria. It provides evidence that levels of GAM may be underestimated in north-west CAR in areas experiencing conflict. These findings highlight the need for targeted nutritional support to reach children most at risk of malnutrition. CHWs are a proven effective means of delivering essential primary healthcare services in hard-to-reach, conflict-affected areas.