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How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
The exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, a...
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Published in: | Pharmaceuticals (Basel, Switzerland) Switzerland), 2023-07, Vol.16 (7), p.1011 |
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description | The exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, and consecutively increase CA-VTE-related morbidity and mortality. In addition, there might be specific clinical problems in the treatment of CA-VTE in patients with oral and facial cancer, such as swallowing difficulties, that might limit the possibilities of oral anticoagulation. Finally, there are limited data regarding the optimal treatment of CA-VTE in patients with oral and facial cancer, and this includes data on novel therapeutic strategies, including the use of direct oral anticoagulants. This article reviews current data on the optimal treatment strategy for CA-VTE in patients with OFC. |
doi_str_mv | 10.3390/ph16071011 |
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Oral and Facial Cancer-Associated Venous Thromboembolism</title><source>PubMed (Medline)</source><source>Publicly Available Content Database</source><creator>Janíčková, Mária ; Bolek, Tomáš ; Stančiaková, Lucia ; Nagy, Norbert ; Mokáň, Marián ; Samoš, Matej</creator><creatorcontrib>Janíčková, Mária ; Bolek, Tomáš ; Stančiaková, Lucia ; Nagy, Norbert ; Mokáň, Marián ; Samoš, Matej</creatorcontrib><description>The exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, and consecutively increase CA-VTE-related morbidity and mortality. In addition, there might be specific clinical problems in the treatment of CA-VTE in patients with oral and facial cancer, such as swallowing difficulties, that might limit the possibilities of oral anticoagulation. Finally, there are limited data regarding the optimal treatment of CA-VTE in patients with oral and facial cancer, and this includes data on novel therapeutic strategies, including the use of direct oral anticoagulants. This article reviews current data on the optimal treatment strategy for CA-VTE in patients with OFC.</description><identifier>ISSN: 1424-8247</identifier><identifier>EISSN: 1424-8247</identifier><identifier>DOI: 10.3390/ph16071011</identifier><identifier>PMID: 37513923</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Anticoagulants ; Blood clots ; Blood platelets ; Cancer therapies ; cancer-associated venous thromboembolism ; Care and treatment ; Catheters ; Clinical medicine ; Clinical practice guidelines ; Complications and side effects ; Diagnosis ; direct oral anticoagulants ; Head and neck cancer ; Hemorrhage ; Leukocytes ; Neutrophils ; oral and facial cancer ; Oral cancer ; Pancreatic cancer ; parenteral anticoagulation ; Patients ; Pulmonary embolisms ; Review ; Risk factors ; Thromboembolism ; Thrombosis</subject><ispartof>Pharmaceuticals (Basel, Switzerland), 2023-07, Vol.16 (7), p.1011</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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Oral and Facial Cancer-Associated Venous Thromboembolism</title><title>Pharmaceuticals (Basel, Switzerland)</title><addtitle>Pharmaceuticals (Basel)</addtitle><description>The exact incidence of cancer-associated venous thromboembolism (CA-VTE) in patients with oral and facial cancer (OFC) is not exactly known, and this risk is empirically considered to be low. However, this suggestion may result in disease underdiagnosis, prolong the initiation of adequate therapy, and consecutively increase CA-VTE-related morbidity and mortality. In addition, there might be specific clinical problems in the treatment of CA-VTE in patients with oral and facial cancer, such as swallowing difficulties, that might limit the possibilities of oral anticoagulation. Finally, there are limited data regarding the optimal treatment of CA-VTE in patients with oral and facial cancer, and this includes data on novel therapeutic strategies, including the use of direct oral anticoagulants. 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Oral and Facial Cancer-Associated Venous Thromboembolism</title><author>Janíčková, Mária ; Bolek, Tomáš ; Stančiaková, Lucia ; Nagy, Norbert ; Mokáň, Marián ; Samoš, Matej</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c499t-abd20921edbe55696a547427c900be5ecf7096037e7c44835e828fb71d4445103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Anticoagulants</topic><topic>Blood clots</topic><topic>Blood platelets</topic><topic>Cancer therapies</topic><topic>cancer-associated venous thromboembolism</topic><topic>Care and treatment</topic><topic>Catheters</topic><topic>Clinical medicine</topic><topic>Clinical practice guidelines</topic><topic>Complications and side effects</topic><topic>Diagnosis</topic><topic>direct oral anticoagulants</topic><topic>Head and neck cancer</topic><topic>Hemorrhage</topic><topic>Leukocytes</topic><topic>Neutrophils</topic><topic>oral and facial cancer</topic><topic>Oral cancer</topic><topic>Pancreatic cancer</topic><topic>parenteral anticoagulation</topic><topic>Patients</topic><topic>Pulmonary embolisms</topic><topic>Review</topic><topic>Risk factors</topic><topic>Thromboembolism</topic><topic>Thrombosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Janíčková, Mária</creatorcontrib><creatorcontrib>Bolek, Tomáš</creatorcontrib><creatorcontrib>Stančiaková, Lucia</creatorcontrib><creatorcontrib>Nagy, Norbert</creatorcontrib><creatorcontrib>Mokáň, Marián</creatorcontrib><creatorcontrib>Samoš, Matej</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Pharmaceuticals (Basel, Switzerland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Janíčková, Mária</au><au>Bolek, Tomáš</au><au>Stančiaková, Lucia</au><au>Nagy, Norbert</au><au>Mokáň, Marián</au><au>Samoš, Matej</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How to Treat Today? 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subjects | Anticoagulants Blood clots Blood platelets Cancer therapies cancer-associated venous thromboembolism Care and treatment Catheters Clinical medicine Clinical practice guidelines Complications and side effects Diagnosis direct oral anticoagulants Head and neck cancer Hemorrhage Leukocytes Neutrophils oral and facial cancer Oral cancer Pancreatic cancer parenteral anticoagulation Patients Pulmonary embolisms Review Risk factors Thromboembolism Thrombosis |
title | How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism |
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