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Normal ventilation/perfusion lung scan in patients with extensive chronic thromboembolism pulmonary hypertension: A case report

Chronic thromboembolism pulmonary hypertension (CTEPH) is a common cause of severe pulmonary hypertension, resulting in significant morbidity and mortality. In patients with unexplained pulmonary hypertension, a ventilation-perfusion (VQ) scan should be considered the initial diagnostic test of choi...

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Bibliographic Details
Published in:Radiology case reports 2019-04, Vol.14 (4), p.510-513
Main Authors: Alduraibi, Alaa, Fathala, Ahmed
Format: Article
Language:English
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Summary:Chronic thromboembolism pulmonary hypertension (CTEPH) is a common cause of severe pulmonary hypertension, resulting in significant morbidity and mortality. In patients with unexplained pulmonary hypertension, a ventilation-perfusion (VQ) scan should be considered the initial diagnostic test of choice. VQ scans are widely available with excellent sensitivity, specificity, and diagnostic accuracy. However, the occurrence of a normal VQ scan in the presence of CTEPH is believed to be rare. In fact, the rate of actual false negatives in VQ scans is unknown because pulmonary digital subtraction angiography and computed tomography pulmonary angiography are rarely performed in patients with a normal VQ scan. This study reports a patient with a high clinical likelihood of CTEPH due to a hypercoagulable state, recurrent deep vein thrombosis, and prior history of acute pulmonary embolism with negative VQ scans. He subsequently underwent pulmonary digital subtraction angiography, which revealed bilateral extensive emboli with partial recanalization of the organized thrombus. The patient underwent successful pulmonary endarterectomy, with marked improvement of his symptoms postoperatively.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2019.01.022