Active rheumatoid arthritis with multiple pulmonary nodules failure to multiple remissive therapy: Which is the solution?

We describe the case of a 63-year-old nonsmoker woman, with a long history of active seropositive rheumatoid arthritis, failure to multiple disease-modifying antirheumatic drugs due to both loss of efficacy and adverse drug reaction. She was exposed to silicon dust some years ago and has many pulmon...

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Bibliographic Details
Published in:Revista română de reumatologie 2021-09, Vol.30 (3), p.125-128
Main Authors: Filipescu, Ileana Cosmina, Man, Milena, Rednic, Simona
Format: Article
Language:English
Subjects:
jak inhibitors
pulmonary nodules
rheumatoid arthritis
synthetic dmards
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Summary:We describe the case of a 63-year-old nonsmoker woman, with a long history of active seropositive rheumatoid arthritis, failure to multiple disease-modifying antirheumatic drugs due to both loss of efficacy and adverse drug reaction. She was exposed to silicon dust some years ago and has many pulmonary nodules, revealed by imaging studies as multiple cavitary lung nodules. Her initial pathological samples were negative for any infections and treatment against tuberculosis and anti-fungal therapy did not improve the appearance of the nodules. After an extensive reevaluation of pulmonary nodules, the Baricitinib treatment was started.
ISSN:1843-0791
2069-6086
DOI:10.37897/RJR.2021.3.7