Development of a concise clinical index for predicting chronic chikungunya arthritis

To evaluate the performance of an instrument for predicting chronic chikungunya arthritis (CCA) in adult patients. A diagnostic test study was conducted and data from 217 confirmed cases of chikungunya virus (CHIKV) illness were analyzed. Two chronic chikungunya arthralgia scales (3-item CCAS-3 and...

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Bibliographic Details
Published in:International journal of infectious diseases 2019-09, Vol.86, p.1-4
Main Authors: Murillo-Zamora, Efrén, Mendoza-Cano, Oliver, Trujillo-Hernández, Benjamín, Guzmán-Esquivel, José, Lugo-Radillo, Agustín, Higareda-Almaraz, Martha Alicia, Evangelista-Salazar, Juan José, Higareda-Almaraz, Enrique, Benítes-Godínez, Verónica
Format: Article
Language:English
Subjects:
Arthralgia
Chikungunya virus
Chronic pain
Predictive value of tests
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Summary:To evaluate the performance of an instrument for predicting chronic chikungunya arthritis (CCA) in adult patients. A diagnostic test study was conducted and data from 217 confirmed cases of chikungunya virus (CHIKV) illness were analyzed. Two chronic chikungunya arthralgia scales (3-item CCAS-3 and 4-item CCAS-4) were constructed. Modest performance of the CCAS-3 scale was documented at the two given cut-off points. A CCAS-4 score ≥3 showed high sensitivity and specificity for predicting the persistence of CCA at 12 months after acute disease. If replicated in other populations, these results could be useful in the medical management of patients with symptomatic CHIKV infection.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2019.06.020