Development of a concise clinical index for predicting chronic chikungunya arthritis

To evaluate the performance of an instrument for predicting chronic chikungunya arthritis (CCA) in adult patients. A diagnostic test study was conducted and data from 217 confirmed cases of chikungunya virus (CHIKV) illness were analyzed. Two chronic chikungunya arthralgia scales (3-item CCAS-3 and...

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Published in:International journal of infectious diseases 2019-09, Vol.86, p.1-4
Main Authors: Murillo-Zamora, Efrén, Mendoza-Cano, Oliver, Trujillo-Hernández, Benjamín, Guzmán-Esquivel, José, Lugo-Radillo, Agustín, Higareda-Almaraz, Martha Alicia, Evangelista-Salazar, Juan José, Higareda-Almaraz, Enrique, Benítes-Godínez, Verónica
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Language:English
Subjects:
Arthralgia
Chikungunya virus
Chronic pain
Predictive value of tests
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cited_by cdi_FETCH-LOGICAL-c466t-dc805be52283fbbd8a3a52a06365ea946fcfef36fec008bcbd84f98045de4eba3
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container_title International journal of infectious diseases
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creator Murillo-Zamora, Efrén
Mendoza-Cano, Oliver
Trujillo-Hernández, Benjamín
Guzmán-Esquivel, José
Lugo-Radillo, Agustín
Higareda-Almaraz, Martha Alicia
Evangelista-Salazar, Juan José
Higareda-Almaraz, Enrique
Benítes-Godínez, Verónica
description To evaluate the performance of an instrument for predicting chronic chikungunya arthritis (CCA) in adult patients. A diagnostic test study was conducted and data from 217 confirmed cases of chikungunya virus (CHIKV) illness were analyzed. Two chronic chikungunya arthralgia scales (3-item CCAS-3 and 4-item CCAS-4) were constructed. Modest performance of the CCAS-3 scale was documented at the two given cut-off points. A CCAS-4 score ≥3 showed high sensitivity and specificity for predicting the persistence of CCA at 12 months after acute disease. If replicated in other populations, these results could be useful in the medical management of patients with symptomatic CHIKV infection.
doi_str_mv 10.1016/j.ijid.2019.06.020
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subjects Arthralgia
Chikungunya virus
Chronic pain
Predictive value of tests
title Development of a concise clinical index for predicting chronic chikungunya arthritis
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