Loading…
Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China
Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating prevalence of the H4 subtype heightens the concern for its zoonotic potential, signaling an urge...
Saved in:
| Published in: | Virology journal 2024-04, Vol.21 (1), p.85-85, Article 85 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | cdi_FETCH-LOGICAL-c549t-c6966b41a18a12d48506c4f93b779e79849f393b92647e980d20a710166ee4363 |
| container_end_page | 85 |
| container_issue | 1 |
| container_start_page | 85 |
| container_title | Virology journal |
| container_volume | 21 |
| creator | He, Jinyue Deng, Jing Wen, Xianxian Yan, Mengyuan Liu, Yang Zhou, Yunqiu Du, XuBin Yang, Han Peng, Xiaobin |
| description | Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating prevalence of the H4 subtype heightens the concern for its zoonotic potential, signaling an urgent need for vigilance.
During the period from December 2021 to November 2023, we collected AIV-related environmental samples and assessed them using a comprehensive protocol that included nucleic acid testing, gene sequencing, isolation culture, and resequencing.
In this study, a total of 934 environmental samples were assessed, revealing a remarkably high detection rate (43.66%, 289/662) of AIV in the live poultry market. Notably, the H4N1 subtype AIV (cs2301) was isolated from the live poultry market and its complete genome sequence was successfully determined. Subsequent analysis revealed that cs2301, resulting from a reassortment event between wild and domesticated waterfowl, exhibits multiple mutations and demonstrates potential for host transfer.
Our research once again demonstrates the significant role of wild and domesticated waterfowl in the reassortment process of avian influenza virus, enriching the research on the H4 subtype of AIV, and emphasizing the importance of proactive monitoring the environment related to avian influenza virus. |
| doi_str_mv | 10.1186/s12985-024-02352-8 |
| format | article |
| fullrecord | <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_5dbd16ec61cd4d7c80b89edd2a03a257</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A789675986</galeid><doaj_id>oai_doaj_org_article_5dbd16ec61cd4d7c80b89edd2a03a257</doaj_id><sourcerecordid>A789675986</sourcerecordid><originalsourceid>FETCH-LOGICAL-c549t-c6966b41a18a12d48506c4f93b779e79849f393b92647e980d20a710166ee4363</originalsourceid><addsrcrecordid>eNptUl2LEzEUHURx1-of8EEGfFGwa74mH09SirqFZcUv8C2kyZ1pyjTZTWaK-utN23VpRULIvTfnnHBvTlU9x-gCY8nfZkyUbKaIsLJpQ6byQXWOBaNTRsiPh0fxWfUk5zVClHChHldnVHKEGqLOK73IsTeDj6E2wdUdBBi8re3KJGMHSD6XNNexra_jFvr6kl3jerb1JtSL0PYjhN-m3vo0Zsi1D_V8FUP32YfuTQl9ME-rR63pMzy7OyfV9w_vv80vp1efPi7ms6upbZgappYrzpcMGywNJo7JBnHLWkWXQigQSjLV0pIpwpkAJZEjyAiMMOcAjHI6qRYHXRfNWt8kvzHpl47G630hpk6bVFrpQTdu6TAHy7F1zAkr0VIqcI4YRA1pRNF6d9C6GZcbcBbCkEx_Inp6E_xKd3GrMUZIovIXk-rVnUKKtyPkQW98ttD3JkAcs6aICqoYI7RAX_4DXccxhTKrPUpKho5RnSkd-NDG8rDdieqZkIqLRsndEC7-gyrLwcbbGKD1pX5CeH1CKJgBfg6dGXPWi69fTrHkgLUp5pygvR8IRnrnR33woy5-1Hs_allIL45HeU_5a0D6B_wL17c</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3037884023</pqid></control><display><type>article</type><title>Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China</title><source>Publicly Available Content Database</source><source>PubMed Central(OpenAccess)</source><creator>He, Jinyue ; Deng, Jing ; Wen, Xianxian ; Yan, Mengyuan ; Liu, Yang ; Zhou, Yunqiu ; Du, XuBin ; Yang, Han ; Peng, Xiaobin</creator><creatorcontrib>He, Jinyue ; Deng, Jing ; Wen, Xianxian ; Yan, Mengyuan ; Liu, Yang ; Zhou, Yunqiu ; Du, XuBin ; Yang, Han ; Peng, Xiaobin</creatorcontrib><description>Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating prevalence of the H4 subtype heightens the concern for its zoonotic potential, signaling an urgent need for vigilance.
During the period from December 2021 to November 2023, we collected AIV-related environmental samples and assessed them using a comprehensive protocol that included nucleic acid testing, gene sequencing, isolation culture, and resequencing.
In this study, a total of 934 environmental samples were assessed, revealing a remarkably high detection rate (43.66%, 289/662) of AIV in the live poultry market. Notably, the H4N1 subtype AIV (cs2301) was isolated from the live poultry market and its complete genome sequence was successfully determined. Subsequent analysis revealed that cs2301, resulting from a reassortment event between wild and domesticated waterfowl, exhibits multiple mutations and demonstrates potential for host transfer.
Our research once again demonstrates the significant role of wild and domesticated waterfowl in the reassortment process of avian influenza virus, enriching the research on the H4 subtype of AIV, and emphasizing the importance of proactive monitoring the environment related to avian influenza virus.</description><identifier>ISSN: 1743-422X</identifier><identifier>EISSN: 1743-422X</identifier><identifier>DOI: 10.1186/s12985-024-02352-8</identifier><identifier>PMID: 38600529</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Amino acids ; Analysis ; Avian flu ; Avian influenza ; Avian influenza viruses ; Distribution ; Genes ; Genetic aspects ; Genomes ; Genomics ; Identification and classification ; Influenza ; Live poultry markets ; Novel multiplex reassortant virus ; Nucleotide sequence ; Poultry ; Risk factors ; Southwest China ; Subtype H4N1 ; Vigilance ; Viruses ; Waterfowl ; Zoonoses ; Zoonotic potential</subject><ispartof>Virology journal, 2024-04, Vol.21 (1), p.85-85, Article 85</ispartof><rights>2024. The Author(s).</rights><rights>COPYRIGHT 2024 BioMed Central Ltd.</rights><rights>2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c549t-c6966b41a18a12d48506c4f93b779e79849f393b92647e980d20a710166ee4363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11008002/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3037884023?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38600529$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>He, Jinyue</creatorcontrib><creatorcontrib>Deng, Jing</creatorcontrib><creatorcontrib>Wen, Xianxian</creatorcontrib><creatorcontrib>Yan, Mengyuan</creatorcontrib><creatorcontrib>Liu, Yang</creatorcontrib><creatorcontrib>Zhou, Yunqiu</creatorcontrib><creatorcontrib>Du, XuBin</creatorcontrib><creatorcontrib>Yang, Han</creatorcontrib><creatorcontrib>Peng, Xiaobin</creatorcontrib><title>Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China</title><title>Virology journal</title><addtitle>Virol J</addtitle><description>Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating prevalence of the H4 subtype heightens the concern for its zoonotic potential, signaling an urgent need for vigilance.
During the period from December 2021 to November 2023, we collected AIV-related environmental samples and assessed them using a comprehensive protocol that included nucleic acid testing, gene sequencing, isolation culture, and resequencing.
In this study, a total of 934 environmental samples were assessed, revealing a remarkably high detection rate (43.66%, 289/662) of AIV in the live poultry market. Notably, the H4N1 subtype AIV (cs2301) was isolated from the live poultry market and its complete genome sequence was successfully determined. Subsequent analysis revealed that cs2301, resulting from a reassortment event between wild and domesticated waterfowl, exhibits multiple mutations and demonstrates potential for host transfer.
Our research once again demonstrates the significant role of wild and domesticated waterfowl in the reassortment process of avian influenza virus, enriching the research on the H4 subtype of AIV, and emphasizing the importance of proactive monitoring the environment related to avian influenza virus.</description><subject>Amino acids</subject><subject>Analysis</subject><subject>Avian flu</subject><subject>Avian influenza</subject><subject>Avian influenza viruses</subject><subject>Distribution</subject><subject>Genes</subject><subject>Genetic aspects</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Identification and classification</subject><subject>Influenza</subject><subject>Live poultry markets</subject><subject>Novel multiplex reassortant virus</subject><subject>Nucleotide sequence</subject><subject>Poultry</subject><subject>Risk factors</subject><subject>Southwest China</subject><subject>Subtype H4N1</subject><subject>Vigilance</subject><subject>Viruses</subject><subject>Waterfowl</subject><subject>Zoonoses</subject><subject>Zoonotic potential</subject><issn>1743-422X</issn><issn>1743-422X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptUl2LEzEUHURx1-of8EEGfFGwa74mH09SirqFZcUv8C2kyZ1pyjTZTWaK-utN23VpRULIvTfnnHBvTlU9x-gCY8nfZkyUbKaIsLJpQ6byQXWOBaNTRsiPh0fxWfUk5zVClHChHldnVHKEGqLOK73IsTeDj6E2wdUdBBi8re3KJGMHSD6XNNexra_jFvr6kl3jerb1JtSL0PYjhN-m3vo0Zsi1D_V8FUP32YfuTQl9ME-rR63pMzy7OyfV9w_vv80vp1efPi7ms6upbZgappYrzpcMGywNJo7JBnHLWkWXQigQSjLV0pIpwpkAJZEjyAiMMOcAjHI6qRYHXRfNWt8kvzHpl47G630hpk6bVFrpQTdu6TAHy7F1zAkr0VIqcI4YRA1pRNF6d9C6GZcbcBbCkEx_Inp6E_xKd3GrMUZIovIXk-rVnUKKtyPkQW98ttD3JkAcs6aICqoYI7RAX_4DXccxhTKrPUpKho5RnSkd-NDG8rDdieqZkIqLRsndEC7-gyrLwcbbGKD1pX5CeH1CKJgBfg6dGXPWi69fTrHkgLUp5pygvR8IRnrnR33woy5-1Hs_allIL45HeU_5a0D6B_wL17c</recordid><startdate>20240410</startdate><enddate>20240410</enddate><creator>He, Jinyue</creator><creator>Deng, Jing</creator><creator>Wen, Xianxian</creator><creator>Yan, Mengyuan</creator><creator>Liu, Yang</creator><creator>Zhou, Yunqiu</creator><creator>Du, XuBin</creator><creator>Yang, Han</creator><creator>Peng, Xiaobin</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240410</creationdate><title>Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China</title><author>He, Jinyue ; Deng, Jing ; Wen, Xianxian ; Yan, Mengyuan ; Liu, Yang ; Zhou, Yunqiu ; Du, XuBin ; Yang, Han ; Peng, Xiaobin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c549t-c6966b41a18a12d48506c4f93b779e79849f393b92647e980d20a710166ee4363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Amino acids</topic><topic>Analysis</topic><topic>Avian flu</topic><topic>Avian influenza</topic><topic>Avian influenza viruses</topic><topic>Distribution</topic><topic>Genes</topic><topic>Genetic aspects</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Identification and classification</topic><topic>Influenza</topic><topic>Live poultry markets</topic><topic>Novel multiplex reassortant virus</topic><topic>Nucleotide sequence</topic><topic>Poultry</topic><topic>Risk factors</topic><topic>Southwest China</topic><topic>Subtype H4N1</topic><topic>Vigilance</topic><topic>Viruses</topic><topic>Waterfowl</topic><topic>Zoonoses</topic><topic>Zoonotic potential</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>He, Jinyue</creatorcontrib><creatorcontrib>Deng, Jing</creatorcontrib><creatorcontrib>Wen, Xianxian</creatorcontrib><creatorcontrib>Yan, Mengyuan</creatorcontrib><creatorcontrib>Liu, Yang</creatorcontrib><creatorcontrib>Zhou, Yunqiu</creatorcontrib><creatorcontrib>Du, XuBin</creatorcontrib><creatorcontrib>Yang, Han</creatorcontrib><creatorcontrib>Peng, Xiaobin</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Virology journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>He, Jinyue</au><au>Deng, Jing</au><au>Wen, Xianxian</au><au>Yan, Mengyuan</au><au>Liu, Yang</au><au>Zhou, Yunqiu</au><au>Du, XuBin</au><au>Yang, Han</au><au>Peng, Xiaobin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China</atitle><jtitle>Virology journal</jtitle><addtitle>Virol J</addtitle><date>2024-04-10</date><risdate>2024</risdate><volume>21</volume><issue>1</issue><spage>85</spage><epage>85</epage><pages>85-85</pages><artnum>85</artnum><issn>1743-422X</issn><eissn>1743-422X</eissn><abstract>Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating prevalence of the H4 subtype heightens the concern for its zoonotic potential, signaling an urgent need for vigilance.
During the period from December 2021 to November 2023, we collected AIV-related environmental samples and assessed them using a comprehensive protocol that included nucleic acid testing, gene sequencing, isolation culture, and resequencing.
In this study, a total of 934 environmental samples were assessed, revealing a remarkably high detection rate (43.66%, 289/662) of AIV in the live poultry market. Notably, the H4N1 subtype AIV (cs2301) was isolated from the live poultry market and its complete genome sequence was successfully determined. Subsequent analysis revealed that cs2301, resulting from a reassortment event between wild and domesticated waterfowl, exhibits multiple mutations and demonstrates potential for host transfer.
Our research once again demonstrates the significant role of wild and domesticated waterfowl in the reassortment process of avian influenza virus, enriching the research on the H4 subtype of AIV, and emphasizing the importance of proactive monitoring the environment related to avian influenza virus.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>38600529</pmid><doi>10.1186/s12985-024-02352-8</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1743-422X |
| ispartof | Virology journal, 2024-04, Vol.21 (1), p.85-85, Article 85 |
| issn | 1743-422X 1743-422X |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_5dbd16ec61cd4d7c80b89edd2a03a257 |
| source | Publicly Available Content Database; PubMed Central(OpenAccess) |
| subjects | Amino acids Analysis Avian flu Avian influenza Avian influenza viruses Distribution Genes Genetic aspects Genomes Genomics Identification and classification Influenza Live poultry markets Novel multiplex reassortant virus Nucleotide sequence Poultry Risk factors Southwest China Subtype H4N1 Vigilance Viruses Waterfowl Zoonoses Zoonotic potential |
| title | Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T06%3A37%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Isolation%20and%20genetic%20characteristics%20of%20Novel%20H4N1%20Avian%20Influenza%20viruses%20in%20ChongQing,%20China&rft.jtitle=Virology%20journal&rft.au=He,%20Jinyue&rft.date=2024-04-10&rft.volume=21&rft.issue=1&rft.spage=85&rft.epage=85&rft.pages=85-85&rft.artnum=85&rft.issn=1743-422X&rft.eissn=1743-422X&rft_id=info:doi/10.1186/s12985-024-02352-8&rft_dat=%3Cgale_doaj_%3EA789675986%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c549t-c6966b41a18a12d48506c4f93b779e79849f393b92647e980d20a710166ee4363%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3037884023&rft_id=info:pmid/38600529&rft_galeid=A789675986&rfr_iscdi=true |