Gum hypertrophy - an unusual presenting feature in a case of precursor T-cell acute lymphoblastic leukemia

Acute lymphoblastic leukemia/lymphoma, the malignant transformation of T-cell or B-cell precursors, is the most common diagnosis in pediatric oncology. Precursor T-cell acute lymphoblastic leukemia/lymphoma commonly affects adolescents, and is associated with mediastinal mass in over half of the cas...

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Bibliographic Details
Published in:Turkish journal of haematology 2008-12, Vol.25 (4), p.201-204
Main Authors: Premalata, Chennagiri Srinivasamurthy, Madhumati, Davanam Satyanarayana, Lakshmidevi, Vishweshwariah, Pradeep, Rudramurthy, Appaji, Lingappa, Mukherjee, Geetashree
Format: Article
Language:English
Subjects:
gum
jaw
oral cavity
Precursor T-ALL
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Summary:Acute lymphoblastic leukemia/lymphoma, the malignant transformation of T-cell or B-cell precursors, is the most common diagnosis in pediatric oncology. Precursor T-cell acute lymphoblastic leukemia/lymphoma commonly affects adolescents, and is associated with mediastinal mass in over half of the cases, with early dissemination to bone marrow, gonads and the central nervous system. We present a rare case of precursor T-cell acute lymphoblastic leukemia/lymphoma with initial oral manifestation, presenting with the unusual features of gum hypertrophy and involvement of upper jaw and palate in a 10-year-old boy. This report discusses the clinical presentation, histopathologic and immunologic features, and diagnosis of this malignancy.
ISSN:1300-7777
1308-5263