Comprehensive analysis of the prognostic value of pre-treatment nutritional indicators in elderly rectal cancer patients

Nutritional status assessment has been deemed essential in treating elderly cancer patients. This study aims to investigate and compare the prognostic value and clinical utility of pre-treatment nutritional indicators in elderly rectal cancer (RC) patients. We retrospectively collected data from 361...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2024-09, Vol.14 (1), p.22078-15, Article 22078
Main Authors: Qiu, Jianjian, Yu, Yilin, Wang, Zhiping, Hong, Liang, Shao, Lingdong, Wu, Junxin
Format: Article
Language:English
Subjects:
631/67/1504/1885
692/499
692/700/1750
692/700/2814
Aged
Aged, 80 and over
Body Mass Index
Colorectal cancer
Elderly rectal cancer patients
Female
Geriatric Assessment - methods
Health risks
Humanities and Social Sciences
Humans
Lung cancer
Male
Medical prognosis
Mortality risk
multidisciplinary
Nutrition
Nutrition Assessment
Nutrition indicators
Nutritional Status
Patients
Pre-treatment nutritional risk assessment
Prognosis
Prognosis analysis
Rectal Neoplasms - diagnosis
Rectal Neoplasms - mortality
Rectal Neoplasms - therapy
Rectum
Retrospective Studies
Risk groups
Risk stratification
ROC Curve
Science
Science (multidisciplinary)
Survival
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nutritional status assessment has been deemed essential in treating elderly cancer patients. This study aims to investigate and compare the prognostic value and clinical utility of pre-treatment nutritional indicators in elderly rectal cancer (RC) patients. We retrospectively collected data from 361 elderly rectal cancer patients. The optimal cut-off values for pre-treatment nutritional indicators were calculated using ROC curve analysis. Univariate and multivariate Cox analyses were conducted to identify independent prognostic nutritional indicators. The predictive performance and clinical utility of these independent nutritional indicators was evaluated using time-dependent ROC. Multivariate analyses showed that body mass index (BMI), prognostic nutritional index (PNI), geriatric nutrition risk index (GNRI), and platelet-albumin ratio (PAR) independently predicted overall survival and progression-free survival in elderly RC patients (all p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-73123-2