EFFECTIVENESS OF VISCOSUPPLEMENTATION IN THE TREATMENT OF HEMOPHILIC ARTHROPATHY: A SYSTEMATIC REVIEW

To describe the efficacy of using viscosupplementation in patients with hemophilic arthropathy (HA), on pain, limb functionality, and quality of life. A systematic review of the literature was performed following the PRISMA guidelines without limitations of language or year of publication. The searc...

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Bibliographic Details
Published in:Acta ortopedica brasileira 2023-01, Vol.31 (6), p.e271857-e271857
Main Authors: Martins, Samilly Conceição Maia, DE Andrade, Erion, Silva, Mayara Branco E, Ozelo, Margareth Castro, Campos, Gustavo Constantino DE, Pagnano, Rodrigo Gonçalves
Format: Article
Language:English
Subjects:
Arthropathy
Hemarthrosis
Hemophilia
Hyaluronic Acid
Original
ORTHOPEDICS
Pain Management
Viscosupplementation
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Summary:To describe the efficacy of using viscosupplementation in patients with hemophilic arthropathy (HA), on pain, limb functionality, and quality of life. A systematic review of the literature was performed following the PRISMA guidelines without limitations of language or year of publication. The search was performed on the following medical databases: PubMed, Cochrane Library, EMBASE, BVS/BIREME, Scopus, Web of Science, EBSCOhost, and PROQUEST in April 2020. The search used the following word: (hemophilia AND joint diseases) OR (haemophilic arthropathy OR hemophilic arthropathy) AND viscosupplementation. The systematic review identified 127 articles, 10 of which were selected for data extraction and qualitative analysis. The 10 selected articles included 297 joints with HA in 177 hemophilic subjects. Our review showed positive results in alleviating pain and improving functional capacity, and quality of life. No major adverse effects were observed. There is a lack of scientific evidence regarding viscosupplementation with hyaluronic acid, but the results presented in this research suggest that it is an effective and safe therapeutic option to alleviate pain and improve functional capacity in patients with HA.
ISSN:1413-7852
1809-4406
1809-4406
DOI:10.1590/1413-785220233105E271857