Quality of Life of Celiac Patients in Brazil: Questionnaire Translation, Cultural Adaptation and Validation

• Published in: Nutrients 2018-08, Vol.10 (9), p.1167
• Main Authors: Pratesi, Claudia P, Häuser, Winfred, Uenishi, Rosa Harumi, Selleski, Nicole, Nakano, Eduardo Yoshio, Gandolfi, Lenora, Pratesi, Riccardo, Zandonadi, Renata Puppin
• Format: Article
• Language: English
• Subjects: Adaptation; Adult; Autoimmune diseases; Bilingualism; Brazil; Brazilian CD-QoL; Celiac disease; Celiac Disease - diagnosis; Celiac Disease - diet therapy; Celiac Disease - physiopathology; Celiac Disease - psychology; Cost of Illness; Cultural Characteristics; Diet; Diet, Gluten-Free; Early Diagnosis; Education; Emotions; Female; Gluten; Health Knowledge, Attitudes, Practice; Health sciences; Humans; Interpreters; Male; Medical personnel; Mental depression; Mental Health; Nutrition research; Patients; Predictive Value of Tests; Professionals; Quality of Life; questionnaire; Questionnaires; Reproducibility of Results; Semantics; Socioeconomic factors; Statistical analysis; Surveys and Questionnaires; Systematic review; Translating; Translations
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu10091167

(1) Background: Celiac disease (CD) is a common autoimmune disorder. The manifestations of the disease and the obligatory life-long gluten-free diet (GFD) are associated with the impairment of patients' quality of life. Therefore, the present study aimed to translate, culturally adapt and validate a celiac disease quality of life (CD-QoL) questionnaire and apply it to a representative number of Brazilian CD patients. (2) Methods: A cross-cultural Brazilian-Portuguese version of the CD-QoL was developed according to revised international guidelines. The questionnaire was administered to 450 celiac patients. The reliability, reproducibility and validity were studied. (3) Results: The Brazilian CD-QoL questionnaire presents valid measures of reproducibility and internal consistency. Early diagnosis is related to higher scores of Brazilian CD-QoL social, sub- and total scale. There was a positive correlation between higher education level and higher QoL. Individuals with partners tend to have a better emotional subscale of QoL. CD-patients who follow a strict GFD have highest QoL scale values. Men scored higher than women on the CD-QoL. All results were statistically significant except for the gastrointestinal subscale. (4) Conclusions: Brazilian CD-QoL allows comparative research between different celiac populations in the world. QoL research will help in the development of effective strategies to improve Brazilian celiac patients' quality of life.