Emulating a Target Trial of Early Compared to Late Initiation of Appropriate Antibiotic Therapy for Hospital-acquired Monobacterial Gram-negative Blood Stream Infections

Considering the difficulties and ethical concerns to conduct a randomized controlled trial comparing early appropriate antimicrobial treatment (

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Bibliographic Details
Published in:Journal of global antimicrobial resistance. 2024-12, Vol.39, p.7-8
Main Authors: Aslan, Abdullah Tarik, Ezure, Yukiko, Tanriverdi, Elif Seren, Dag, Osman, Cimen, Cansu, Otlu, Baris, Harris, Patrick, Akova, Murat, Paterson, David L.
Format: Article
Language:English
Subjects:
early appropriate therapy
emulation
Gram-negative bacteraemia
mortality
Target trial
Online Access:Get full text
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Description
Summary:Considering the difficulties and ethical concerns to conduct a randomized controlled trial comparing early appropriate antimicrobial treatment (
ISSN:2213-7165
DOI:10.1016/j.jgar.2024.10.020