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Chromosomal damage in air crew members of international flights: A preliminary report

Air crew members of international flights are exposed to ionizing radiations originated from the collision of cosmic particles with atoms of the atmosphere. The degree of exposure varies according to the altitude, latitude, and solar activity. The cytogenetical analysis showed a significant increase...

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Published in:Genetics and molecular biology 2000-12, Vol.23 (4), p.1117-1120
Main Authors: Picco, S.J., De Luca, J.C., MacIntyre, C., Dulout, F.N.
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description Air crew members of international flights are exposed to ionizing radiations originated from the collision of cosmic particles with atoms of the atmosphere. The degree of exposure varies according to the altitude, latitude, and solar activity. The cytogenetical analysis showed a significant increase of dicentric chromosomes (14.5 ± 0.76 per 1,000 cells) in active air crew members as well as in retired air crew members (7.5 ± 0.59 per 1,000 cells) in relation to controls (0.5 ± 0.05 per 1,000 cells). In active members the frequency of ring chromosomes was also increased (2.0 ± 0.31 per 1,000 cells) but not found in retired crew members. These observations suggest a high degree of exposure to ionizing radiations of air crew personnel. Consequently, the cytogenetic follow-up of air crews chronically exposed to low radiation doses is an open field for further investigations. Tripulantes de vôos internacionais estão expostos a radiações ionizantes originadas da colisão de partículas cósmicas com átomos da atmosfera. O grau de exposição varia de acordo com a altitude, latitude e a atividade solar. A análise citogenética mostrou um aumento significante no número de cromossomos dicêntricos (14,5 ± 0,76 por 1000 células) em membros ativos da tripulação, assim como em tripulantes aposentados (7,5 ± 0,59 por 1000 células), em relação a controles (0,5 ± 0,05 por 1000 células). Em tripulantes em atividade a freqüência de cromossomos em anel também aumentou (2,0 ± 0,31 por 1000 células), mas isso não ocorreu em tripulantes aposentados. Estas observações sugerem um alto grau de exposição do pessoal de bordo a radiações ionizantes. Conseqüentemente, o acompanhamento citogenético de tripulantes de aviões cronicamente expostos a baixas doses de radiação é um campo aberto para futuras investigações.
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Mol. Biol</addtitle><date>2000-12-01</date><risdate>2000</risdate><volume>23</volume><issue>4</issue><spage>1117</spage><epage>1120</epage><pages>1117-1120</pages><issn>1415-4757</issn><issn>1678-4685</issn><eissn>1415-4757</eissn><eissn>1678-4685</eissn><abstract>Air crew members of international flights are exposed to ionizing radiations originated from the collision of cosmic particles with atoms of the atmosphere. The degree of exposure varies according to the altitude, latitude, and solar activity. The cytogenetical analysis showed a significant increase of dicentric chromosomes (14.5 ± 0.76 per 1,000 cells) in active air crew members as well as in retired air crew members (7.5 ± 0.59 per 1,000 cells) in relation to controls (0.5 ± 0.05 per 1,000 cells). In active members the frequency of ring chromosomes was also increased (2.0 ± 0.31 per 1,000 cells) but not found in retired crew members. These observations suggest a high degree of exposure to ionizing radiations of air crew personnel. Consequently, the cytogenetic follow-up of air crews chronically exposed to low radiation doses is an open field for further investigations. Tripulantes de vôos internacionais estão expostos a radiações ionizantes originadas da colisão de partículas cósmicas com átomos da atmosfera. O grau de exposição varia de acordo com a altitude, latitude e a atividade solar. A análise citogenética mostrou um aumento significante no número de cromossomos dicêntricos (14,5 ± 0,76 por 1000 células) em membros ativos da tripulação, assim como em tripulantes aposentados (7,5 ± 0,59 por 1000 células), em relação a controles (0,5 ± 0,05 por 1000 células). Em tripulantes em atividade a freqüência de cromossomos em anel também aumentou (2,0 ± 0,31 por 1000 células), mas isso não ocorreu em tripulantes aposentados. Estas observações sugerem um alto grau de exposição do pessoal de bordo a radiações ionizantes. Conseqüentemente, o acompanhamento citogenético de tripulantes de aviões cronicamente expostos a baixas doses de radiação é um campo aberto para futuras investigações.</abstract><pub>Sociedade Brasileira de Genética</pub><doi>10.1590/S1415-47572000000400061</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
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GENETICS & HEREDITY
title Chromosomal damage in air crew members of international flights: A preliminary report
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