Akkermansia muciniphila and Faecalibacterium prausnitzii in Immune-Related Diseases

Probiotics and synbiotics are used to treat chronic illnesses due to their roles in immune system modulation and anti-inflammatory response. They have been shown to reduce inflammation in a number of immune-related disorders, including systemic lupus erythematosus (SLE), human immunodeficiency virus...

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Bibliographic Details
Published in:Microorganisms (Basel) 2022-11, Vol.10 (12), p.2382
Main Authors: Effendi, Raden Mohamad Rendy Ariezal, Anshory, Muhammad, Kalim, Handono, Dwiyana, Reiva Farah, Suwarsa, Oki, Pardo, Luba M, Nijsten, Tamar E C, Thio, Hok Bing
Format: Article
Language:English
Subjects:
Akkermansia
Akkermansia muciniphila
Atopic dermatitis
Bacteria
Cancer
Cancer immunotherapy
Chronic conditions
Chronic illnesses
Dermatitis
Digestive system
Disease
Disorders
Faecalibacterium
Faecalibacterium prausnitzii
Gastrointestinal tract
HIV
Homeostasis
Human immunodeficiency virus
Immune system
immune-related diseases
Immunological diseases
Immunology
Immunotherapy
Inflammation
Inflammatory bowel disease
Inflammatory response
Intestinal microflora
Metabolism
Metabolites
Microbiomes
Microbiota
Microorganisms
Nervous system
Physiology
Prebiotics
Probiotics
Psoriasis
Review
Skin diseases
Systemic lupus erythematosus
Therapeutic targets
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Summary:Probiotics and synbiotics are used to treat chronic illnesses due to their roles in immune system modulation and anti-inflammatory response. They have been shown to reduce inflammation in a number of immune-related disorders, including systemic lupus erythematosus (SLE), human immunodeficiency virus (HIV), and chronic inflammatory skin conditions such as psoriasis and atopic dermatitis (AD). ( ) and ( ) are two different types of bacteria that play a significant part in this function. It has been established that and are abundant in normal populations and have protective benefits on digestive health while also enhancing the immune system, metabolism, and gut barrier of the host. They have the potential to be a therapeutic target in diseases connected to the microbiota, such as immunological disorders and cancer immunotherapy. There has not been a review of the anti-inflammatory effects of and , particularly in immunological diseases. In this review, we highlight the most recent scientific findings regarding and as two significant gut microbiota for microbiome alterations and seek to provide cutting-edge insight in terms of microbiome-targeted therapies as promising preventive and therapeutic tools in immune-related diseases and cancer immunotherapy.
ISSN:2076-2607
2076-2607
DOI:10.3390/microorganisms10122382