Weight-for-age distributions among children with HIV on antiretroviral therapy in the International epidemiology Databases to Evaluate AIDS (IeDEA) multiregional consortium

Pediatric antiretroviral therapy (ART) for children with HIV (CHIV) must be dosed appropriately for children's changing weights as they grow. To inform accurate estimates of ART formulations and doses needed, we described weight-for-age distributions among CHIV on ART in the IeDEA global pediat...

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Bibliographic Details
Published in:BMC research notes 2020-05, Vol.13 (1), p.249-249, Article 249
Main Authors: Jesson, Julie, Desmonde, Sophie, Yiannoutsos, Constantin T, Patten, Gabriela, Malateste, Karen, Duda, Stephany N, Kumarasamy, Nagalingeswaran, Yotebieng, Marcel, Davies, Mary-Ann, Musick, Beverly, Leroy, Valeriane, Ciaranello, Andrea
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Acquired Immunodeficiency Syndrome - drug therapy
Acquired Immunodeficiency Syndrome - epidemiology
Adolescent
Africa, Central
Africa, Eastern
Africa, Southern
Age
Age Distribution
AIDS
Anti-HIV Agents - therapeutic use
Antiretroviral agents
Antiretroviral drugs
Antiretroviral formulation
Antiretroviral therapy
Asia, Southeastern
Bias
Caribbean Region
Central America
Child
Child, Preschool
Children
Children & youth
Cohort Studies
Consortia
Databases, Factual
Dosage and administration
Drug therapy
Epidemiology
Female
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV patients
Human immunodeficiency virus
Humans
Infant
Male
Mortality
Pediatric antiretroviral therapy
Pediatric diseases
Pediatric HIV
Pediatrics
Population
Research Note
South America
Teenagers
Trends
Weight-for-age
World Health Organization
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Summary:Pediatric antiretroviral therapy (ART) for children with HIV (CHIV) must be dosed appropriately for children's changing weights as they grow. To inform accurate estimates of ART formulations and doses needed, we described weight-for-age distributions among CHIV on ART in the IeDEA global pediatric collaboration between 2004 and 2016, using data from six regions (East, West, Central, and Southern Africa, Asia-Pacific, and Central/South America and the Caribbean). Overall, 59,862 children contributed to the analysis. Age and weight data were available from 530,080 clinical encounters for girls and 537,894 for boys. For each one-year age stratum from 0 to 15 years, we calculated the proportion of children in each of the weight bands designated by the World Health Organization as relevant to pediatric ART formulations: 0 to  
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-020-05081-7