Dynamic modeling of cost-effectiveness of rotavirus vaccination, Kazakhstan

The government of Kazakhstan, a middle-income country in Central Asia, is considering the introduction of rotavirus vaccination into its national immunization program. We performed a cost-effectiveness analysis of rotavirus vaccination spanning 20 years by using a synthesis of dynamic transmission m...

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Bibliographic Details
Published in:Emerging infectious diseases 2014-01, Vol.20 (1), p.29-37
Main Authors: Freiesleben de Blasio, Birgitte, Flem, Elmira, Latipov, Renat, Kuatbaeva, Ajnagul, Kristiansen, Ivar Sønbø
Format: Article
Language:English
Subjects:
Adolescent
Adult
Analysis
Child
Child, Preschool
Cost-Benefit Analysis
cost-effectiveness
dynamic modeling
Economic aspects
Gastroenteritis
Health aspects
herd immunity
Humans
Immunization Programs - economics
Incidence
Infant
Infant, Newborn
Kazakhstan - epidemiology
Middle Aged
rotavirus
Rotavirus - immunology
Rotavirus Infections - economics
Rotavirus Infections - epidemiology
Rotavirus Infections - prevention & control
Rotavirus Vaccines - economics
Rotavirus Vaccines - immunology
Vaccination
Vaccination - economics
viruses
Young Adult
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Summary:The government of Kazakhstan, a middle-income country in Central Asia, is considering the introduction of rotavirus vaccination into its national immunization program. We performed a cost-effectiveness analysis of rotavirus vaccination spanning 20 years by using a synthesis of dynamic transmission models accounting for herd protection. We found that a vaccination program with 90% coverage would prevent ≈880 rotavirus deaths and save an average of 54,784 life-years for children
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2001.130019