A Double-Blind Randomized Placebo-Controlled Feasibility Study Evaluating Individualized Homeopathy in Managing Pain of Knee Osteoarthritis

Few homeopathic complexes seemed to produce significant effects in osteoarthritis; still, individualized homeopathy remained untested. We evaluated the feasibility of conducting an efficacy trial of individualized homeopathy in osteoarthritis. A prospective, parallel-arm, double-blind, randomized, p...

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Bibliographic Details
Published in:Journal of evidence-based complementary & alternative medicine 2015-07, Vol.20 (3), p.186-191
Main Authors: Koley, Munmun, Saha, Subhranil, Ghosh, Shubhamoy
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Double-Blind Method
Feasibility Studies
Female
Homeopathy - methods
Humans
India
Male
Middle Aged
Osteoarthritis, Knee - physiopathology
Pain Management - methods
Pain Measurement
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Summary:Few homeopathic complexes seemed to produce significant effects in osteoarthritis; still, individualized homeopathy remained untested. We evaluated the feasibility of conducting an efficacy trial of individualized homeopathy in osteoarthritis. A prospective, parallel-arm, double-blind, randomized, placebo-controlled pilot study was conducted from January to October 2014 involving 60 patients (homeopathy, n = 30; placebo, n = 30) who were suffering from acute painful episodes of knee osteoarthritis and visiting the outpatient clinic of Mahesh Bhattacharyya Homeopathic Medical College and Hospital, West Bengal, India. Statistically significant reduction was achieved in 3 visual analog scales (measuring pain, stiffness, and loss of function) and Osteoarthritis Research Society International scores in both groups over 2 weeks (P < .05); however, group differences were not significant (P > .05). Overall, homeopathy did not appear to be superior to placebo; still, further rigorous evaluation in this design involving a larger sample size seems feasible in future. Trial registration: Clinical Trials Registry, India (CTRI/2014/05/004589).
ISSN:2156-5872
2156-5899
DOI:10.1177/2156587214568668