Construction of a predictive model and prognosis of left ventricular systolic dysfunction in patients with sepsis based on the diagnosis using left ventricular global longitudinal strain

Cardiac dysfunction, a common complication of sepsis, is associated with increased mortality. However, its risk factors are poorly understood, and a predictive model might help in the management of cardiac dysfunction. A monocentric prospective study of patients with sepsis was performed. Left ventr...

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Bibliographic Details
Published in:Journal of intensive care 2022-06, Vol.10 (1), p.29-29, Article 29
Main Authors: Yu, Jiangquan, Zheng, Ruiqiang, Yang, Penglei, Wang, Daxin
Format: Article
Language:English
Subjects:
Analysis
Atrial fibrillation
Blood pressure
Body temperature
Canada
Cardiac arrhythmia
Cardiovascular disease
Complications and side effects
Congenital diseases
Echocardiography
Ejection fraction
Heart attacks
Heart failure
Heart rate
Infection
Intensive care
Intubation
Lactates
Left ventricle global longitudinal strain
Left ventricular systolic dysfunction
Length of stay
Medical diagnosis
Medical prognosis
Medical research
Medicine, Experimental
Mortality
Myocarditis
Natriuretic peptides
Nomograms
Patients
Predictive model
Risk factors
Sepsis
Software
Survival analysis
Work stations
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Summary:Cardiac dysfunction, a common complication of sepsis, is associated with increased mortality. However, its risk factors are poorly understood, and a predictive model might help in the management of cardiac dysfunction. A monocentric prospective study of patients with sepsis was performed. Left ventricular global longitudinal strain (LV GLS) was measured using echocardiography within 72 h of the patients diagnosed with sepsis, and the patients were categorized into two groups: LV GLS > -17%, left ventricular systolic dysfunction group (LVSD group); and LV GLS ≤ -17%, non-left ventricular systolic dysfunction group (Non-LVSD group). The baseline characteristics and prognosis of the two groups were analyzed. Based on the results of the multivariate logistic regression analysis, a predictive model of LVSD was established and a nomogram was drawn. Fifty-one left ventricular systolic dysfunction in patients with sepsis and 73 non-LVSD sepsis patients were included. Prognostic analysis showed that patients with LVSD had higher ICU mortality, in-hospital mortality, the incidence of atrial fibrillation (P 
ISSN:2052-0492
2052-0492
DOI:10.1186/s40560-022-00621-8