The neuroprotective effects of human growth hormone as a potential treatment for amyotrophic lateral sclerosis

Human growth hormone（GH）is a single-chain polypeptide of 191 amino acids that is involved in the regulation of various physiological processes,such as growth and metabolism.GH is synthesized and secreted by somatotropic cells in the anterior pituitary gland.Its secretion is primarily regulated by a...

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Bibliographic Details
Published in:Neural regeneration research 2015-08, Vol.10 (8), p.1201-1203
Main Authors: Chung, Jin-Young, Sunwoo, Jun-Sang, Kim, Min-Wook, Kim, Manho
Format: Article
Language:English
Subjects:
Amyotrophic lateral sclerosis
Analysis
Apoptosis
Binding sites
Care and treatment
Cell cycle
Cell growth
Disease
Genes
Genetic aspects
Glucose
Growth hormones
Health aspects
Highlights
Hypoxia
Insulin resistance
Insulin-like growth factors
Kinases
Metabolism
Neurodegeneration
Neurogenesis
Oxidative stress
Phosphorylation
Physiology
Pituitary gland
Proteins
Signal transduction
Somatotropin
Stem cells
Traumatic brain injury
人生长激素
平衡调节
氨基酸组成
生理过程
生长激素释放激素
硬化
神经保护作用
细胞分泌
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Summary:Human growth hormone（GH）is a single-chain polypeptide of 191 amino acids that is involved in the regulation of various physiological processes,such as growth and metabolism.GH is synthesized and secreted by somatotropic cells in the anterior pituitary gland.Its secretion is primarily regulated by a balance between growth hormone-releasing hormone and growth hormone-inhibiting hormone,
ISSN:1673-5374
1876-7958
DOI:10.4103/1673-5374.162690