Microbiome in Multiple Sclerosis; Where Are We, What We Know and Do Not Know

An increase of multiple sclerosis (MS) incidence has been reported during the last decade, and this may be connected to environmental factors. This review article aims to encapsulate the current advances targeting the study of the gut-brain axis, which mediates the communication between the central...

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Bibliographic Details
Published in:Brain sciences 2020-04, Vol.10 (4), p.234
Main Authors: Boziki, Marina Kleopatra, Kesidou, Evangelia, Theotokis, Paschalis, Mentis, Alexios-Fotios A, Karafoulidou, Eleni, Melnikov, Mikhail, Sviridova, Anastasia, Rogovski, Vladimir, Boyko, Alexey, Grigoriadis, Nikolaos
Format: Article
Language:English
Subjects:
Central nervous system
Disease
disease-modifying treatments
Environmental factors
gut microbiome
gut–brain axis
Intestinal microflora
Lifestyles
Metabolism
Metabolites
metagenomics
Microbiomes
Microbiota
Microorganisms
Minority & ethnic groups
Multiple sclerosis
Pathogenesis
Patients
Review
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Summary:An increase of multiple sclerosis (MS) incidence has been reported during the last decade, and this may be connected to environmental factors. This review article aims to encapsulate the current advances targeting the study of the gut-brain axis, which mediates the communication between the central nervous system and the gut microbiome. Clinical data arising from many research studies, which have assessed the effects of administered disease-modifying treatments in MS patients to the gut microbiome, are also recapitulated.
ISSN:2076-3425
2076-3425
DOI:10.3390/brainsci10040234