Prevalence of cryptococcosis in Atlántico, department of Colombia assessed with an active epidemiological search

Cryptococcosis is the second most frequent cause of opportunistic infections in human immunodeficiency virus (HIV) patients in Colombia. We aimed to determine the prevalence of cryptococcosis in the Colombian department of Atlántico. An active search for cryptococcosis cases was conducted between 20...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical 2019-01, Vol.52, p.e20180194-e20180194
Main Authors: Noguera, María Clara, Escandón, Patricia, Arévalo, Merle, García, Yina, Suárez, Luz Estela, Castañeda, Elizabeth
Format: Article
Language:English
Subjects:
Active epidemiological search
Adolescent
Adult
Annual prevalence
Child
Colombia
Colombia - epidemiology
Cryptococcosis
Cryptococcosis - epidemiology
Cryptococcosis - microbiology
Cryptococcus gattii
Cryptococcus gattii - isolation & purification
Cryptococcus neoformans
Cryptococcus neoformans - isolation & purification
Female
Genotype
Humans
Male
Middle Aged
Molecular Typing
Phenotype
Prevalence
TROPICAL MEDICINE
Young Adult
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Summary:Cryptococcosis is the second most frequent cause of opportunistic infections in human immunodeficiency virus (HIV) patients in Colombia. We aimed to determine the prevalence of cryptococcosis in the Colombian department of Atlántico. An active search for cryptococcosis cases was conducted between 2015 and 2017 in health institutions by distributing surveys to clinicians and characterizing samples phenotypically and genotypically. Thirty-eight cryptococcosis cases were identified (81.6% men, 76.3% HIV patients). The calculated annual prevalence was 5.08/1 million inhabitants. Cryptococcus neoformans var. grubii VNI was isolated in 34 cases. These results provide the basis for passive surveillance of cryptococcosis.
ISSN:0037-8682
1678-9849
1678-9849
DOI:10.1590/0037-8682-0194-2018