The tumor volume after radical prostatectomy and its clinical impact on the prognosis of patients with localized prostate cancer

We evaluated the contribution of tumor volume (TV) to localized prostate cancer (PCa) patients’ prognosis. We retrospectively analyzed the data of 2394 patients who underwent radical prostatectomy (RP) for localized PCa. The effect of TV and tumor prostate ratio (TV/PV) on PCa patients' prognos...

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Bibliographic Details
Published in:Scientific reports 2022-04, Vol.12 (1), p.6003-6003, Article 6003
Main Authors: Yuk, Hyeong Dong, Byun, Seok-Soo, Hong, Sung Kyu, Lee, Hakmin
Format: Article
Language:English
Subjects:
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Cancer surgery
Classification
Disease-Free Survival
Humanities and Social Sciences
Humans
Male
Medical prognosis
multidisciplinary
Neoplasm Recurrence, Local - pathology
Patients
Prognosis
Prostate - pathology
Prostate - surgery
Prostate cancer
Prostate-Specific Antigen
Prostatectomy
Prostatic Neoplasms - pathology
Prostatic Neoplasms - surgery
Retrospective Studies
Science
Science (multidisciplinary)
Seminal vesicle
Seminal Vesicles - pathology
Tumor Burden
Tumors
Urological surgery
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Summary:We evaluated the contribution of tumor volume (TV) to localized prostate cancer (PCa) patients’ prognosis. We retrospectively analyzed the data of 2394 patients who underwent radical prostatectomy (RP) for localized PCa. The effect of TV and tumor prostate ratio (TV/PV) on PCa patients' prognosis was analyzed through Kaplan–Meier and Cox-proportional analysis. The mean prostate volume for all patients was 36.5 ± 15.4 cc, and the mean TV was 5.9 ± 8.3 cc. A significant positive relationship was observed between the classification by risk group in D’ Amico risk classification and the National Comprehensive Cancer Network risk group (P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-09431-2