Metabolic evaluation of first-time uncomplicated renal stone formers: A prospective study

• Published in: Current urology 2023-03, Vol.17 (1), p.36-40
• Main Authors: Ranjan, Satish Kumar, Mittal, Ankur, Mirza, Anissa Atif, Kumar, Sunil, Panwar, Vikas Kumar, Navriya, Shivcharan, Mandal, Arup Kumar, Mammen, Kim Jacob
• Format: Article
• Language: English
• Subjects: Special Topic: Advances in Urinary Calculi Management: Original
• ISSN: 1661-7649; 1661-7657
• DOI: 10.1097/CU9.0000000000000169

BackgroundNephrolithiasis is a global health problem. The recurrence rate after the first stone clearance is approximately 50% at 5 years. Metabolic abnormalities are an important factor responsible for stone recurrence. Our prevalidated study aimed to evaluate metabolic abnormalities associated with first-time uncomplicated renal stone formers (FTURSF). Materials and methodsIn this prospective, exploratory, time-bound, descriptive study, 30 first-time renal stone formers were evaluated for metabolic abnormalities. High-risk stone formers were excluded from the study. Data were collected in a predefined proforma, transferred to an Excel sheet, and analyzed using the Statistical Package for Social Sciences 20 and Epi Info 7. Fisher exact test, Mann-Whitney U test, paired t test, and Pearson correlation coefficient were used for statistical analyses. ResultsThe mean age of the participants was 35.57 ± 11.07 years, with a male-to-female ratio of 1.72. The most common abnormality was a 24-hour urine volume of