Microparticles as Novel Biomarkers and Therapeutic Targets in Coronary Heart Disease

INTRODUCTION Microparticles （MPs） were increased in patients with coronary heart disease （CHD）,with the subtypes and quantity of MPs variate in different types of CHD.There were emerging reports indicating that MPs may play important roles in the pathogenesis of CHD.Here in this review we summarized...

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Bibliographic Details
Published in:Chinese medical journal 2015-01, Vol.128 (2), p.267-272
Main Authors: Zhou, Bo-Da, Guo, Ge, Zheng, Le-Min, Zu, Ling-Yun, Gao, Wei
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Angiogenesis
Anticoagulants
Apoptosis
Biological markers
Biomarkers
Biomarkers - blood
Blood platelets
Cardiology
Cardiovascular disease
Care and treatment
Cell-Derived Microparticles - metabolism
Coagulation
Coronary Heart Disease
Endothelial Function
Inflammation
Microparticle
Coronary Disease - blood
Coronary heart disease
Coronary vessels
Diabetes
Diagnosis
Education
Endothelium
Gene therapy
Health aspects
Heart attacks
Hospitals
Humans
Hypertension
Inflammation - blood
Laboratories
Metabolic syndrome
Molecular biology
Nitric oxide
Pathogenesis
Peptides
Political aspects
冠心病
冠状动脉
微粒
心脏疾病
治疗
生物标记
血管内皮功能
靶点
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Description
Summary:INTRODUCTION Microparticles （MPs） were increased in patients with coronary heart disease （CHD）,with the subtypes and quantity of MPs variate in different types of CHD.There were emerging reports indicating that MPs may play important roles in the pathogenesis of CHD.Here in this review we summarized the pro-inflammation,pro-coagulation effects of MPs,as well as their impacts on endothelial function and angiogenesis.MPs have the potential of being powerful diagnostic biomarkers and therapeutic tools in CHD patients in the future.
ISSN:0366-6999
2542-5641
DOI:10.4103/0366-6999.149231