C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement

• Published in: Revista brasileira de cirurgia cardiovascular 2022-01, Vol.37 (3), p.292-300
• Main Authors: Katkat, Fahrettin, Kalyoncuoglu, Muhsin, Ozcan, Sevgi, Tugrul, Sevil, Abanus, Hanife, Ince, Orhan, Balli, Mehmet, Sahin, Irfan, Okuyan, Ertugrul
• Format: Article
• Language: English
• Subjects: Aortic Stenosis; C-Reactive Protein; CARDIAC & CARDIOVASCULAR SYSTEMS; Mortality; Original; Serum Albumin; SURGERY; Transcatheter Aortic Valve Replacement
• ISSN: 1678-9741; 0102-7638; 1678-9741
• DOI: 10.21470/1678-9741-2020-0482

We aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR). This study was retrospectively designed and includes 170 TAVR patients with a mean age of 78.4±7.1 years. Patients were divided into 2 groups as those who died and those who survived, taking into account the follow-up period. Complete blood count, serum CRP and serum albumin were obtained on admission. The CAR value of all patients was calculated and the relationship of CAR with early (≤30 days) and late mortality (>30 days) was evaluated. The median follow-up period was 19 [7-31] months (maximum 66 months). Early mortality was observed in 20 (11.8%) patients, whereas late mortality was observed in 39 (22.9%) patients, most of them male (61.1%, P=0.04). Non-survivors had greater CAR value, higher baseline serum CRP level and lower baseline albumin level than survivors (P