The Effect of Selective Laser Trabeculoplasty on Intraocular Pressure in Patients with Dexamethasone Intravitreal Implant-Induced Elevated Intraocular Pressure

Introduction. To assess the safety and efficacy of selective laser trabeculoplasty (SLT) for ocular hypertension (OHT) induced by a dexamethasone (DEX) intravitreal implant. Materials and Methods. We performed a retrospective study of patients who underwent an SLT procedure for ocular hypertension i...

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Bibliographic Details
Published in:Journal of ophthalmology 2020-10, Vol.2020 (2020), p.1-6
Main Authors: Nordmann, Jean-Philippe, Labbé, Antoine, Keilani, Chafik, Rodallec, Thibaut, Adam, Raphaël, Akesbi, Jad, Theillac, Vincent, Bennedjai, Amin, Blumen-Ohana, Esther
Format: Article
Language:English
Subjects:
Central nervous system depressants
Demographics
Dexamethasone
Diabetes
Diabetic retinopathy
Edema
Extracellular matrix
Eye
Eye surgery
Gene expression
Glaucoma
Human health and pathology
Laboratories
Lasers
Life Sciences
Medical research
Medicine, Experimental
Patients
Povidone
Sensory Organs
Steroids
Surgery
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Summary:Introduction. To assess the safety and efficacy of selective laser trabeculoplasty (SLT) for ocular hypertension (OHT) induced by a dexamethasone (DEX) intravitreal implant. Materials and Methods. We performed a retrospective study of patients who underwent an SLT procedure for ocular hypertension induced by injection of a DEX intravitreal implant. Patients had, at least, one injection of the DEX-implant for symptomatic macular edema. SLT was delivered to 360° of the trabecular meshwork in two sessions. The primary outcome was a decrease in IOP, evaluated at one, three, and six months after the SLT procedure. Results. Twenty-six eyes of 22 patients were included. The mean intraocular pressure (IOP) measured after DEX-implant injection was 25.4 ± 5.4 mmHg, and the mean increase in IOP was 35.8 ± 14.6%. The mean follow-up after SLT was 18.3 ± 7.7 months. After SLT, the mean IOP dropped by 30.9% at one month (16.9 ± 4.5 mmHg, p=0.01), 33.6% at three months (16.0 ± 2.7 mmHg, p
ISSN:2090-004X
2090-0058
DOI:10.1155/2020/3439182